Chemical ablation of the gallbladder

Xu, Zhi; Wang, L.; Zhang, N.; Ling, Xiaofeng; Hou, Chunsheng; Zhou, Xiaosi

doi:10.1007/s00464-004-8221-6

Cited by 22 publications

(3 citation statements)

References 13 publications

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“…Historically, there have been several studies that have investigated the feasibility of gallbladder ablation in animal models and human cholecystitis patients with various chemical agents, such as acetic acid, alcohol, and sodium hypochlorite as well as heat and laser modalities, occasionally with pre-ablation cystic duct embolization. 27 28 29 30 31 32 Some of these studies have demonstrated success, however, issues included ineffective or incomplete mucosal ablation, mucocele formation, requirement for several ablation sessions, and mucosal regeneration. 33 To our knowledge, the only multi-patient study over the last decade to investigate gallbladder chemical ablation is a prospective study of 10 acute cholecystitis patients performed recently by Atar et al 32 Patients first underwent percutaneous cholecystostomy tube replacement followed by clearance of existing bile duct stones into the duodenum before undergoing cystic duct embolization with coils.…”

Section: Gallbladder Ablationmentioning

confidence: 99%

Percutaneous Interventions for Symptomatic Cholelithiasis and Acute Cholecystitis

Ragulojan

Fradkin

D’Souza

2022

Digestive Disease Interventions

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Laparoscopic cholecystectomy is considered the standard treatment option for symptomatic cholelithiasis and acute cholecystitis. However, in non-surgical candidates or patients meeting criteria of severe presentation, percutaneous cholecystostomy is the recommended approach to management, generally with the intent of eventual cholecystectomy. Should interval cholecystectomy not be an option, additional novel percutaneous techniques for stone extraction and/or gallbladder ablation have shown success in the recent literature and, along with cholecystostomy, are presented in this review.

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Section: Gallbladder Ablationmentioning

confidence: 99%

Percutaneous Interventions for Symptomatic Cholelithiasis and Acute Cholecystitis

Ragulojan

Fradkin

D’Souza

2022

Digestive Disease Interventions

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“…Becker et al showed the feasibility of ablation in a porcine model using electrocoagulation for cystic duct ablation, and repeated cycles of 95% EtOH and 3% STS to ablate the gallbladder, subsequently attempted in 8 patients [4,6]. A second series of 34 patients treated similarly had limited success [9]. Boiling contrast (76% diatrizoate meglumine and sodium) and catheter-based thermoablation of the gallbladder had limited success [8].…”

mentioning

confidence: 96%

“…Clinical Findings/Procedure Details: Early chemical sclerosing agents attempted in animal gallbladders included EtOH, 3% sodium tetradecyl sulfate (STS), tetracycline, trifluoroacetic acid, NaOH, hydrogen peroxide, phenol, methyl cyanoacrylate, morrhuate sodium solution, and sodium carbonate. Complications included spillage of sclerosing agent, gallbladder rupture, incomplete ablation, and abscess/mucocele formation [9][10]. Becker et al showed the feasibility of ablation in a porcine model using electrocoagulation for cystic duct ablation, and repeated cycles of 95% EtOH and 3% STS to ablate the gallbladder, subsequently attempted in 8 patients [4,6].…”

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confidence: 99%

What interventional radiologists need to know about treatment response guidelines in oncologic imaging

Rezai

Arslan

Soni³

2016

Journal of Vascular and Interventional Radiology

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Learning Objectives: The goal of this educational exhibit is to provide an overview of treatment response guidelines relevant to interventional radiologists. Being familiar with organ specific and non-organ specific treatment response evaluation guidelines is crucial for optimal assessment and planning for subsequent therapies. Background: Imaging-based evaluation of tumor response is an important aspect of oncology. Most treatment modalities offered by interventional radiologists are cytostatic in nature and do not necessarily cause a decrease in size of neoplasm in response to treatment. Interventional radiologists should be familiar with response evaluation guidelines for optimal assessment of response. Clinical Findings/Procedure Details: Different imaging guidelines for evaluation of treatment response are discussed with emphasis on those most relevant to interventional radiologists. An overview of anatomical imaging biomarkers of treatment response such as WHO and RECIST guidelines and volumetric evaluation is provided. Functional biomarkers of treatment response such as PET will be reviewed. Liverspecific biomarkers of treatment response such as mRECIST, EASL and Choi criteria will be discussed. Conclusions: A brief overview of imaging biomarkers of treatment response is provided to ensure optimal assessment and planning in interventional oncology. References1. Salem R, Thurston KG. Radioembolization with 90Yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 1: Technical and methodologic considerations. J Vasc Interv Radiol 2006; 17(8):1251-1278. 2. Tochetto SM, Rezai P, Rezvani M, et al. Does multidetector CT attenuation change in colon cancer liver metastases treated with 90Y help predict metabolic activity at FDG PET? Radiology 2010; 255(1):164-172. 3. Galizia MS, Tore HG, Chalian H, McCarthy R, Salem R, Yaghmai V. MDCT necrosis quantification in the assessment of hepatocellular carcinoma response to yttrium 90 radioembolization therapy: comparison of twodimensional and volumetric techniques. Acad Radiol 2012; 19(1):48-54. 4. Yaghmai V, Miller FH, Rezai P, Benson AB, 3rd, Salem R. Response to treatment series: part 2, tumor response assessment-using new and conventional criteria. AJR Am J Roentgenol 2011; 197(1):18-27. Educational Exhibit Abstract No. 572 Percutaneous gallbladder ablation: from boiling contrast to cryotherapy-what we have learned and have yet to discover

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Endoscopic Management of Gallbladder Stones: Can We Eliminate Cholecystectomy?

Yeung

Teoh

2016

Curr Gastroenterol Rep

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The gold standard for the management of acute cholecystitis is laparoscopic cholecystectomy. In patients that are not fit for surgery, percutaneous cholecystostomy is the standard treatment. However, the procedure is only a temporary measure for controlling gallbladder symptoms and it is frequently associated with morbidities. Recently, endoscopic options for management of acute cholecystitis have been developed. The approach avoids the need for a percutaneous drain and may allow endoscopic treatment of the gallstone. The aim of this article is to provide an overview on the current status of endoscopic management of acute cholecystitis.

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Chemical ablation of the gallbladder

Abstract: Minicholecystostomy followed by chemical ablation of the gallbladder was a safe, effective, and simple procedure for treating high-risk patients with acute cholecystitis and/or cholelithiasis.

Cited by 22 publications

References 13 publications

Percutaneous Interventions for Symptomatic Cholelithiasis and Acute Cholecystitis

Percutaneous Interventions for Symptomatic Cholelithiasis and Acute Cholecystitis

What interventional radiologists need to know about treatment response guidelines in oncologic imaging

Endoscopic Management of Gallbladder Stones: Can We Eliminate Cholecystectomy?

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