CHEMFET Devices for biomedical and environmental applications

Barbaro, A.; Colapicchioni, C.; Davini, Enrico; Mazzamurro, Giuseppina; Piotto, Andrea; Porcelli, Fernando

doi:10.1002/adma.19920040605

Cited by 18 publications

(4 citation statements)

References 60 publications

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“…These roles will be discussed in detail below. However, many reviews have previously been published on the subject of CP-based biosensors employing enzymes. − As such, our coverage here will focus on key findings and the most recent literature.…”

Section: B Embedded or Attached Redox-active Enzyme-based Sensorsmentioning

confidence: 99%

Conjugated Polymer-Based Chemical Sensors

2000

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Section: B Embedded or Attached Redox-active Enzyme-based Sensorsmentioning

confidence: 99%

Conjugated Polymer-Based Chemical Sensors

2000

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“…Field effect transistors have been adapted to chemical sensors (ChemFETs) by incorporation into an electrochemical cell. 37,38 They can also be made into biosensors by coating the sensing surface with a biological agent such as described above for penicillin. 39 The light addressable potentiometric sensor (LAPS) determines the surface potential optically by means of the photovoltaic effect.…”

Section: Conductometry Conductometric Detection Monitorsmentioning

confidence: 99%

Electrochemical biosensors

2010

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Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. The biological component in the sensor recognizes its analyte resulting in a catalytic or binding event that ultimately produces an electrical signal monitored by a transducer that is proportional to analyte concentration. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial, and agricultural applications. The two classes of electrochemical biosensors, biocatalytic devices and affinity sensors, will be discussed in this critical review to provide an accessible introduction to electrochemical biosensors for any scientist (110 references).

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“…pH-ISFETs are the most common proton transducers that are being covered with polymeric membranes. The selectivity of a resulting CHEMFET depends on the ionophore incorporated into the polymeric membrane. ,,,− The origin of the CHEMFET's signal is the potential difference arising at the membrane/aqueous solution interface due to the complexation of the ion carrier with the analyte ion at the outer-phase boundary of the membrane. No significant changes are reported to occur at the inner membrane boundary and the internal interface between the polymeric membrane and the FET's gate.…”

mentioning

confidence: 99%

Ion-Partitioning Membrane-Based Electrochemical Sensors

Moschou

Chaniotakis

2000

Anal. Chem.

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The application of ion-partitioning membranes on proton transducers for the development of electrochemical sensors is presented. The ion-partitioning membrane incorporates two different ionophores, one selective to protons and the other to analyte cations, as well as the necessary anionic lipophilic sites. As dictated by the electroneutrality principle, when the concentration of the analyte cations in the sample increases, the analyte cations are extracted into the membrane, displacing protons of equal charge out of the membrane. The pH-sensitive gate of a CHEMFET or the surface of a glass pH electrode is used as an internal transducer for the monitoring of the membrane proton flux. The resulting signal of the pH transducer is related to the concentration of the analyte cation present in the sample. The experiments presented here indicate that the observed CHEMFET's signal is affected by the interaction of the pH-sensitive sensor element with protons released by the polymeric membrane.

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CHEMFET Devices for biomedical and environmental applications

Cited by 18 publications

References 60 publications

Conjugated Polymer-Based Chemical Sensors

Conjugated Polymer-Based Chemical Sensors

Electrochemical biosensors

Ion-Partitioning Membrane-Based Electrochemical Sensors

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