Cheating Death: A Rare Case Presentation of Kratom Toxicity

Abstract

Kratom is a psychoactive herb that has been gaining widespread popularity due to its ease of availability and opiate-like effects. While it has been used beneficially as a method of weaning off opiate addictions, it does have a host of toxic effects when misused or abused. There has been a wide spectrum of negative effects including renal failure, liver failure, and cardiac toxicity. While some adverse effects have been reversed with medical intervention, others left more of a detrimental long-term impact not amenable to even the most invasive therapies. We present the case of a patient who was admitted to the intensive care unit after presenting with unresponsiveness secondary to a cerebrovascular accident, rhabdomyolysis, and renal failure. The patient had begun using kratom, initially for recreational purposes, and later escalating it to abusive doses. The patient survived the episode after suffering many complications including transient reversible nonischemic cardiomyopathy and was discharged in a neurologically stable state; however, he ended up being hemodialysis-dependent at such an early age. Rhabdomyolysis is a rare complication of this herb that has not been well documented.

Kratom abuse as an emerging issue of addiction, overdose toxicities and deaths: a review

“…While some effects have been successfully managed with medical intervention, others left long-term morbidities. Patel et al (2021) reported a case cerebrovascular accident, transient nonischemic reversible cardiomyopathy rhabdomyolysis, and irreversible renal failure following abusive doses of kratom.…”