Chauffage par effet plasmon pour la désorption localisée de cellules capturées sur une biopuce

Abstract

Photo-thermal Effect for Localized Desorption of Primary Lymphocytes Arrayed on an Antibody/DNA-based Biochip)This work proposes a miniaturized system able to perform multiple cell capture followed by cell-type selective release from a biochip surface. Unlabeled lymphocytes are first specifically captured onto a DNA array by antibody-DNA conjugates. The immobilized cells are subsequently released under spatiotemporal control within local heating generated by intense Surface Plasmon Resonance (SPR) produced by laser illumination.