Chasing the suspect: keratoconus

Validation of an Objective Scoring System for Forme Fruste Keratoconus Detection and Post-LASIK Ectasia Risk Assessment in Asian Eyes

“…1,2 A major challenge for any corneal or refractive surgeon is the detection of keratoconus at its earliest stages. 3,4 Various risk assessment and keratoconus detection systems have been described, 2,5,6 but no system is able to detect all cases of FFKC and predict unequivocally the risk of developing keratectasia after LASIK. Although it is important to have a heightened awareness of "at-risk" patients, it is also necessary to avoid overzealously excluding patients who may safely benefit from the life-changing spectacle and contact lens independence that LASIK provides.…”

“…The fellow eye that has no clinical findings of any sort except for certain topographical changes should carry the diagnosis of forme fruste keratoconus." 3 We adhered to these definitions and have chosen such eyes for our study.…”

Screening for Ectasia Risk: What Are We Screening For and How Should We Screen For It?

“…Such cases have been designated as "forme fruste keratoconus" (FFKC) by Klyce 5 and others. Other reasonable alternatives are cases with progressive ectasia after laser vision correction with no identifi able agreed-upon risk factors.…”

Four discriminant models for detecting keratoconus pattern using Zernike coefficients of corneal aberrations

“…This leads to protrusion of the cornea that causes irregular astigmatism, resulting in reduced vision [1,2]. The prognosis of deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus (KC) is good [3,4], but with the advances in refractive surgery, it is crucial to detect KC in its early stage [5][6][7]. Early detection is also important to prevent KC progression by the use of collagen cross-linking surgery [8].…”