Charge-transfer chemistry of azithromycin, the antibiotic used worldwide to treat the coronavirus disease (COVID-19). Part II: Complexation with several π-acceptors (PA, CLA, CHL)

Organic Charge‐Transfer Complexes for Near‐Infrared‐Triggered Photothermal Materials

“…against COVID-19 theoretically. [107][108][109][110][111] Although these studies have not nevertheless concerned with virus experiments, they reveal the existence of antiviral problems of the CTCs and attract researchers.…”

Charge-transfer complexation of TCNE with azithromycin, the antibiotic used worldwide to treat the coronavirus disease (COVID-19). Part IV: A comparison between solid and liquid interactions

“…We believe providing new insight into the CT chemistry of AZM will help researchers and physicians alike to improve the treatment protocols for COVID-19. As a continuation of our previous works [67] , [68] , [69] that aim to furnish a big-picture perspective on the CT chemistry of azithromycin by examining its complexation with several acceptors (σ- and π-) and the resultant CTCs, in this work, we examine the CT interaction between AZM (donor) and tetracyanoethylene (TCNE; acceptor) in both the solid-solid and liquid-liquid states. The solid-solid interaction generated a solid CT complex by grinding solid AZM and TCNE powders together without adding any solvents, while the liquid-liquid interaction also resulted in a solid CT complex but by mixing acetonitrile solutions of AZM and TCNE and filtering off the formed precipitate.…”

Charge-transfer chemistry of two corticosteroids used adjunctively to treat COVID-19. Part I: Complexation of hydrocortisone and dexamethasone donors with DDQ acceptor in five organic solvents

“…Reactions that involve the transfer of an electronically charged particle from an electron-rich donor (D) molecule to an electron-deficient acceptor (A) molecule (D → A) are known as charge transfer (CT) complexations or donor–acceptor interactions [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] . The unique physical, biological, chemical properties of the products resulting from CT interactions have gained the attention of researchers in both basic (physics, chemistry, biochemistry, biology) and applied (engineering, material science, industry, technology, pharmacology, medicine) sciences [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] , [66] , [67] , [68] , [69] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] , [78] , [79] , [80] , [21] ,…”