Charge, hydrophobic and spatial matching in the association of fluorescent reagents with ionic surfactants in aqueous solutions

Klovak, Viktoriia; Kulichenko, S. A.; Lelyushok, Serhii

doi:10.1007/s11696-020-01498-3

Cited by 4 publications

(9 citation statements)

References 20 publications

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“…Previous studies showed the non-monotonic nature of the effect of hydrophobicity and spatial characteristics of reagents and surfactants on the surfactant analytical signal. 9,24 It was also established that the highest values of the analytical signal of ionic surfactants are recorded when the electrostatic attraction between associate-forming particles is realized. 10 At the same time, the maximum values of the analyte fluorescence signal are observed when the opposite charges of the reagent and surfactant are close.…”

Section: Resultsmentioning

confidence: 94%

“…The complex, often non-monotonic, nature of the influence of the hydrophobicity, and spatial characteristics of reagents and surfactants on the surfactant analytical signal is explained by signal amplification under the conditions of “charge” and “spatial-hydrophobic” matching between the reagent and the analyte. 9 This non-monotonic, sometimes extreme, effect was monitored for stoichiometric, sub-stoichiometric, micellar concentrations of the analyte, for pure aqueous solutions of reagent–surfactant associates and in the presence of a surfactant-modifier. 10 Highly hydrophobic rhodamine 6G is optimal among the tested reagents for the hydrophobic ionic compounds determination.…”

Section: Resultsmentioning

confidence: 99%

“…10 Highly hydrophobic rhodamine 6G is optimal among the tested reagents for the hydrophobic ionic compounds determination. 9,10,24…”

Section: Resultsmentioning

confidence: 99%

“…9,10 Electroneutral associates, which are poorly soluble in water and capable of colloidal aggregation, sub-stoichiometric surfactant or reagent-excess associates, formed mainly due to hydrophobic interactions in the system, are also formed in the reagent–surfactant system. 2,9,10…”

Section: Introductionmentioning

confidence: 99%

“…Studies have shown the expediency and advantages of using rhodamine 6G (R6G) and its associates with hydrophobic anionic surfactants. 9,10,24 Such a choice is made considering the pI of the protein and the form of existence of the reagent under the appropriate conditions.…”

Section: Introductionmentioning

confidence: 99%

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Rhodamine 6G–Anionic Surfactant System Modified by Triton X-100 for Fluorescence Determination of Albumin

2023

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The influence of sodium hexadecyl sulfate on the nature of the fluorescence spectra of rhodamine 6G in an aqueous solution and a solution of nonionic Triton X-100 was investigated. The change in the nature of the emission spectra is explained by the formation of hydrophobic stoichiometric and substoichiometric reagent-surfactant associates. Stabilization of the colloid-chemical state and reduction of the total turbidity of rhodamine 6G – anionic surfactants associates solutions with the addition of nonionic surfactant as a modifier were registered. The method of modification of the rhodamine 6G – sodium hexadecyl sulfate system with a nonionic surfactant was used in the development of conditions for the fluorescence determination of protein substances in physiological solutions. The concentration conditions for the use of the modified reagent system rhodamine 6G – anionic surfactant – nonionic surfactant for the fluorescence determination of albumin in urine were optimized.

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Section: Resultsmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

“…10 Highly hydrophobic rhodamine 6G is optimal among the tested reagents for the hydrophobic ionic compounds determination. 9,10,24…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Rhodamine 6G–Anionic Surfactant System Modified by Triton X-100 for Fluorescence Determination of Albumin

2023

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Matching Effects in the Interaction of Ionic Surfactants with Fluorescent Reagents in Micellar Solutions of Triton X-100

Klovak

Kulichenko

Lelyushok

2021

MOCA

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The influence of cationic and anionic surfactant solutions on the character of the fluorescence spectra of reagents of different charge and hydrophobicity in aqueous solutions of nonionic surfactant Triton X-100 has been studied. An increase in the fluorescence intensity and a shift in the position of the fluorescence maximum with increasing hydrophobicity of reagents and ionic surfactants have been shown. The analytical signal of the surfactant is further amplified in the proximity of the charge values of the reagent and the counterion of the surfactant. The non-monotonic nature of the hydrophobicity effect of cationic surfactants on their analytical signal in the system has been shown. The observed effects are explained by the realization of charge and hydrophobic matching in the interaction of surfactants with the fluorescent reagents. The obtained effects are significant in the design of fluorescent systems for the determination and study of surfactant micelles. Conditions for detecting the content of cetylpyridinium chloride by reaction with eosin Y and sodium tetradecyl sulfate by reaction with rhodamine 6G in the presence of Triton X-100 were proposed. The methods have been tested in detecting the content of the ionic surfactants in pharmaceuticals.

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Smart Colorimetric Determination of Ionic Surfactants with Bromothymol Blue at the Presence of Nonionic Surfactant Triton X-100

Korzhan,

Kulichenko,

Lelyushok

2023

MOCA

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The application of digital colorimetry for the determination of ionic surfactants, moderately hydrophobic medicinal substances of ionic nature in the system with bromothymol blue (BTB) in aqueous solutions using a smartphone has been shown. The influence of the solution nonionic surfactant Triton X-100 (TX-100) on the parameters of the colorimetric determination of bromothymol blue has been studied. It was established that the addition of TX-100 improves the linearity of the graduation dependence of the colorimetric signal of bromothymol blue (r ˃ 0.99) and reduces the detection limit of the dye by 15 %. The optimal conditions for the colorimetric determination of the cationic surface-active substance cetylpyridinium chloride (CPC), reagent concentration, and pH were established (LOD = 2.5·10-6 mol L-1, Sr ˂ 2 %). The spike recovery method checked the trueness of the results obtained in the model solutions analysis. The procedure for determining CPC in the drug "Septolete Total" was verified by the addition technique. The ability of a nonionic surface-active substance to stabilize the colloidal chemical state of solutions of hydrophobic counterions associates was used for the colorimetric determination of the anionic surfactant sodium dodecyl sulfate (r = 0.99; LOD = 7.5·10-7 mol L-1) and the less hydrophobic indomethacin (LOD = 6.6·10-6 mol L-1) with the BTB-TX-100-CPC reagent system.

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Charge, hydrophobic and spatial matching in the association of fluorescent reagents with ionic surfactants in aqueous solutions

Cited by 4 publications

References 20 publications

Rhodamine 6G–Anionic Surfactant System Modified by Triton X-100 for Fluorescence Determination of Albumin

Rhodamine 6G–Anionic Surfactant System Modified by Triton X-100 for Fluorescence Determination of Albumin

Matching Effects in the Interaction of Ionic Surfactants with Fluorescent Reagents in Micellar Solutions of Triton X-100

Smart Colorimetric Determination of Ionic Surfactants with Bromothymol Blue at the Presence of Nonionic Surfactant Triton X-100

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