Charcot's triad

Frossard, Jean Louis; Bonvin, Florent

doi:10.1186/1865-1380-4-18

Cited by 6 publications

(9 citation statements)

References 6 publications

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“…Diagnosis of acute cholangitis was based on the presence of fever, leucocytosis, abdominal pain, corroborating diagnostic imaging (ultrasound or computed tomography) and jaundice/hyperbilirubinemia with or without the presence of purulent drainage during ERCP/ percutaneous intervention/surgery and/or positive blood or biliary cultures in patients with risk factors for intermittent biliary obstruction. 11,12 These published criteria were consistent with the Tokyo guidelines. 13 All infections met CDC criteria for intra-abdominal infection.…”

Section: Methodsmentioning

confidence: 76%

“…The median LOS was 17 days for survivors and the median survival duration (i.e. LOS) was 8 (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) for nonsurvivors (P < 0.001). One hundred and eighty-three patients (70%) survived to ICU discharge while 163 (63%) survived to hospital discharge (primary endpoint).…”

Section: Participants and Descriptive Datamentioning

confidence: 99%

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The impact of delayed biliary decompression and anti‐microbial therapy in 260 patients with cholangitis‐associated septic shock

Karvellas

Abraldes

Zepeda-Gómez

et al. 2016

Aliment Pharmacol Ther

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Patients with septic shock secondary to acute cholangitis have significant mortality. Endoscopic biliary decompression >12 h after the onset of shock and delayed receipt of appropriate anti-microbial therapy were both significantly associated with adverse hospital outcome. This might suggest that early initiation of anti-microbial therapy and urgent biliary decompression (within 12 h) could potentially improve outcomes in this high-risk patient population.

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Section: Methodsmentioning

confidence: 76%

Section: Participants and Descriptive Datamentioning

confidence: 99%

The impact of delayed biliary decompression and anti‐microbial therapy in 260 patients with cholangitis‐associated septic shock

Karvellas

Abraldes

Zepeda-Gómez

et al. 2016

Aliment Pharmacol Ther

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“…Charcot's triad of fever, abdominal pain and jaundice are seen in both conditions and warrants consideration in patients presenting with biliary ascariasis 9. The commonest cause of cholestatic jaundice in developing countries is choledocolithiasis.…”

Section: Discussionmentioning

confidence: 99%

Obstructive jaundice induced by biliary ascariasis

Keating

Quigley

Genterola³

2012

BMJ Case Reports

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Ascaris lumbricoides is one of the most prevalent parasitic infections, especially in developing countries. Its presence can lead to a multitude of presentations, one of the rarer ones being obstructive jaundice due to migration of the worm in to the biliary tree. We describe a case of a man who presented as an emergency to the general surgeons complaining of abdominal pain, fever, jaundice and vomiting. Ultrasound was used and the diagnosis of biliary ascariasis was made. The patient underwent surgery consisting of a cholecystectomy, common bile duct exploration and T-tube choledochostomy. Our report highlights the varied aetiology of obstructive jaundice and the importance of including biliary ascariasis in the differential diagnosis of the jaundiced patient, especially from endemic areas.

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“…It affects approximately 10% to 20% of the adult population in developed countries, and the majority are asymptomatic, with only 2% to 4% of patients becoming symptomatic annually. 37,38 Gallbladder cancer is uncommon, with approximately 5000 cases per year in the United States. 39 …”

Section: Gallbladdermentioning

confidence: 99%

Breast Magnetic Resonance Imaging Incidental Findings

Szabo

2014

Topics in Magnetic Resonance Imaging

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B reast magnetic resonance imaging (MRI) is now an integral part of breast imaging. It makes valuable contributions in high-risk screening; evaluating the extent of disease, positive surgical margins, and response to neoadjuvant chemotherapy; as well as distinguishing postoperative scar from recurrent disease. [1][2][3][4][5][6] Although the examination is focused on the breast, portions of the neck, thorax, and upper abdomen are also visualized. Just as in computed tomography, the issue of the incidental or unexpected finding must be addressed by the reader.The detection of these findings during diagnosis and surveillance often results in additional testing, economic burden, and anxiety for the patient. Most incidentally detected lesions are benign; however, the reader must consider the potential of these findings to be metastases or additional primary tumors. Approximately 5% to 10% of breast cancers are metastatic at the time of diagnosis. 7 Even with significant advances in breast cancer treatment, up to 70% of node-positive breast cancers will relapse and 20% to 30% of women with stage I and II disease will develop distant metastases, occurring approximately 15 years after radiation therapy. 7,8 Therefore, all detected findings must be carefully considered. A recent study demonstrated the bone, lung, and liver to be the most common anatomical sites of distant metastases in patients with breast cancer, with 21.9% presenting with multisite involvement. 9 The exception to this pattern is the basal-like and triple-negative breast cancers, which have a predilection for visceral and central nervous system metastases and infrequently involve bone. 10 Although lesion detection occurs on potentially any sequence, the 3-dimensional fast spoiled gradient echo axial sequence is reported to be superior to the short tau inversion recovery sequence in incidental finding detection (82.8% vs 76.5%). 11 As in computed tomography, the addition of intravenous contrast enhances lesion detection. Rinaldi et al 11 demonstrated the enhanced 3-dimensional fast spoiled gradient echo axial fat-suppressed axial sequence to have greater sensitivity compared with unenhanced images in detecting metastatic lesions, especially those smaller than 10 mm (98.3% vs 79.3%). These lesions are often on the edge of the field of view and require window manipulation for identification. BREASTDuring the initial extent of disease evaluation, it is not uncommon to discover additional breast lesions. Management of ipsilateral breast findings is directed by their morphology, enhancement characteristics, and proximity to the index tumor. Masses found in the contralateral breast during the extent of disease evaluation raise the issue of an additional primary tumor.Studies have reported an incidence of contralateral synchronous malignancy detected by preoperative MRI to be in the range of 3% to 5 %. 12-14 A contralateral metachronous cancer has been reported to develop in 5% to 10% of patients with breast cancer within a 10-year follow-up. 12 This is especia...

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Charcot's triad

Cited by 6 publications

References 6 publications

The impact of delayed biliary decompression and anti‐microbial therapy in 260 patients with cholangitis‐associated septic shock

The impact of delayed biliary decompression and anti‐microbial therapy in 260 patients with cholangitis‐associated septic shock

Obstructive jaundice induced by biliary ascariasis

Breast Magnetic Resonance Imaging Incidental Findings

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