Abstract:Cell membranes are largely composed of glycerophospholipids (PL) that create a barrier and separate intracellular aqueous environments. PL are heterogeneous, amphipathic lipids containing a glycerol backbone. In Saccharomyces cerevisiae, our previous work found that 108 different PL structural species were maintained at consistent relative abundance. Our aim is to understand the molecular mechanisms that maintain and regulate PL species abundance. The distribution of acyl chains in PL may be controlled by the … Show more
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