Characterizing m6A Modification Factors and Their Interactions in Colorectal Cancer: Implications for Tumor Subtypes and Clinical Outcomes
Weidong Sun,
Yingchao Su,
Zhiqiang Zhang
Abstract:Background
The study aims to comprehensively combine colorectal cancer data cohorts in order to analyze the effects of various DNA methylation-coding genes on colorectal cancer patients. The annual incidence and mortality of colorectal cancer are very high, and there are no effective treatments for advanced colorectal cancer. DNA methylation is a method widely used to regulate epigenetics in the molecular mechanism study of tumors.
Method
Three single-cell cohorts GSE166555, GSE146771, and EMTAB8107, and fiv… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.