“…Similarly, the efficiency of our image integration method increased with each additional animal completed but remains to be improved; as a comparison, Brooks et al ( 17 ) reported a significant decrease of the fusion time in electrophysiology cases after only 15 patients. Upon availability of novel tools, dedicated devices, and capitalizing on past experiences in cardiovascular navigation ( 18 , 19 , 20 ), the operator’s experience can only improve. In addition to tool guidance, the navigation systems allow the integration of preprocedural data from noninvasive imaging modalities, which can be linked with periprocedural data acquired by the system.…”