Characterizing HIV risk and vulnerability among commercial sex workers in Zaporizhzhya, Ukraine

McLarty, Leigh; Becker, Marissa; Pavlova, Daria; Isak, Shajy; Emmanuel, Faran; Balakireva, O. M.; Bondar, Tetiana; Sazonova, Yana; Sakovych, Olena; Blanchard, James

doi:10.15407/socium2016.01.028

Cited by 2 publications

(1 citation statement)

References 30 publications

(14 reference statements)

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“…The Transitions study is a cross-sectional integrated biological and behavioural survey conceived to measure the prevalence and patterns of HIV risk and vulnerabilities 25,26…”

Section: Study Participants and Sample Collectionmentioning

confidence: 99%

Evaluation of the BioMérieux VIDAS® HIV Duo Quick and Anti-HCV Assays for Dried Blood Spot Based Serosurveillance

Cholette

Farmer

Balakireva³

et al. 2022

Preprint

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Serosurveillance is central to monitoring our progress towards HIV and HCV elimination targets proposed for 2030. However, serosurveillance systems are ineffective without reliable serological assays for the detection of HIV and HCV antibodies. Assays should also be compatible with dried blood spot (DBS) samples to facilitate biological sample collection. The VIDAS® HIV Duo Quick and Anti-HCV assays are sold as reagents strips and processed by the automated VIDAS® benchtop immunoanalyser. While both assays have shown excellent performance in serum and plasma, performance data in DBS samples is lacking. In our study, we evaluate the performance of the VIDAS® HIV Duo Quick and Anti-HCV assays in DBS (n = 725) collected during a cross-sectional serosurvey (the Transitions study). The VIDAS® HIV Duo quick had a sensitivity and specificity of 94.5% (95% CI: 85.1%, 98.5%) and 95.7% (95% CI: 93.9%, 97.0%) respectively. Likewise, the VIDAS® Anti-HCV had a sensitivity and specificity of 95.6% (95% CI: 91.6%, 97.8%) and 95.6% (95% CI: 93.5%, 97.0%) respectively. These assays are unlikely to be helpful in low-prevalence settings due to sub-optimal performance, but their performance could likely be improved by optimizing DBS elution protocols which was, unfortunately, not possible during our study.

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“…The Transitions study is a cross-sectional integrated biological and behavioural survey conceived to measure the prevalence and patterns of HIV risk and vulnerabilities 25,26…”

Section: Study Participants and Sample Collectionmentioning

confidence: 99%

Evaluation of the BioMérieux VIDAS® HIV Duo Quick and Anti-HCV Assays for Dried Blood Spot Based Serosurveillance

Cholette

Farmer

Balakireva³

et al. 2022

Preprint

Self Cite

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Programmatic mapping and size estimation of female sex workers, transgender sex workers and men who have sex with men in İstanbul and Ankara, Turkey

Gökengin

Aybek²,

Aral

et al. 2021

Sex Transm Infect

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ObjectivesDespite a growing HIV threat, there is no definition and characterisation of key populations (KPs), who could be the major drivers of the epidemic in Turkey. We used programmatic mapping to identify locations where KPs congregate, estimate their numbers and understand their operational dynamics to develop appropriate HIV programme implementation strategies.MethodsFemale and transgender sex workers (FSWs and TGSWs), and men who have sex with men (MSM) were studied in İstanbul and Ankara. Within each district, hot spots were identified by interviewing key informants and a crude spot list in each district was developed. The spot validation process was led by KP members who facilitated spot access and interviews of KPs associated with that spot. Final estimates were derived by aggregating the estimated number of KPs at all spots, which was adjusted for the proportion of KPs who visit multiple spots, and for the proportion of KPs who do not visit spots.ResultsFSWs were the largest KP identified in İstanbul with an estimate of 30 447 (5.8/1000 women), followed by 15 780 TGSWs (2.9/1000 men) and 11 656 MSM (2.1/1000). The corresponding numbers in Ankara were 9945 FSWs (5.2/1000 women), 1770 TGSWs (1/1000 men) and 5018 MSM (2.5/1000 men). Each KP had unique typologies based on the way they find and interact with sex partners. MSM were mostly hidden and a higher proportion operated through internet and phone-based applications. Night time was the peak time with Friday, Saturday and Sunday being the peak days of activity in both İstanbul and Ankara.ConclusionsThis study has highlighted the presence of a substantial number of FSWs, TGSW and MSM in İstanbul and Ankara. The information obtained from this study can be used to set priorities for resource allocation and provide HIV prevention services where coverage could be the highest.

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Characterizing HIV risk and vulnerability among commercial sex workers in Zaporizhzhya, Ukraine

Cited by 2 publications

References 30 publications

Evaluation of the BioMérieux VIDAS® HIV Duo Quick and Anti-HCV Assays for Dried Blood Spot Based Serosurveillance

Evaluation of the BioMérieux VIDAS® HIV Duo Quick and Anti-HCV Assays for Dried Blood Spot Based Serosurveillance

Programmatic mapping and size estimation of female sex workers, transgender sex workers and men who have sex with men in İstanbul and Ankara, Turkey

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