Characterization of Venom Components of Two Medically Important Scorpion Species, Hottentota tamulus (Fabricius, 1798) and Androctonus finitimus (Pocock, 1897)

Tahir, Hafız Muhammad; Tobassum, Saadia; Ali, Shaukat; Zahid, Muhammad; Arshad, Muhammad; Gardner, Qurratulann Afza; Ahsan, Muhammad Mohsin

doi:10.2317/0022-8567-93.3.230

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“…Chemical and biological analysis of the scorpion venom revealed some peptides and proteins which are responsible for the sting symptoms (Delgado-Prudencio et al, 2022[ 9 ]; Petricevich, 2010[ 27 ]). High-performance liquid chromatography (HPLC) is one of the suitable instrumental methods to obtain the protein pattern of scorpion venom (Batista et al, 2007[ 2 ]; Tahir et al, 2021[ 33 ]).…”

Section: Introductionmentioning

confidence: 99%

Intraspecific differences in Androctunus crassicauda venom and envenomation symptoms

Safdarian

Vazirianzadeh

Ghorbani

et al. 2022

EXCLI Journal; 21:Doc1222; ISSN 1611-2156

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Envenomation by Androctunus crassicauda is very frequent in Iran, especially in the south-west . This scorpion is one of the six scorpions whose venom is used to prepare anti-venom. Using HPLC, we discovered venom components of A. crassicauda varies from one specimen to another depending on geographical location, and this result is confirmed by those first found in various symptoms of A. crassicauda sting in envenomed persons from two separate geographical places (north and south of Khuzestan province). There was a significant relationship between symptoms and location of envenomation by A. crassicauda . Muscle spasm was more dominant in envenomed people from Northern cities, and venom chromatogram analysis showed the presence of at least six main sharp peaks in Northern A. crassicauda rather than Southern A. crassicauda . It shows intraspecific differences in venom of A. crassicauda that must be considered in treatment of stung people from different geographical locations as well as in the preparation of anti-venom. See also Figure 1 (Fig. 1) .

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