Characterization of transcriptional enhancers in the chicken genome using CRISPR-mediated activation
Jeong Hoon Han,
Hong Jo Lee,
Tae Hyun Kim
Abstract:DNA regulatory elements intricately control when, where, and how genes are activated. Therefore, understanding the function of these elements could unveil the complexity of the genetic regulation network. Genome-wide significant variants are predominantly found in non-coding regions of DNA, so comprehending the predicted functional regulatory elements is crucial for understanding the biological context of these genomic markers, which can be incorporated into breeding programs. The emergence of CRISPR technolog… Show more
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