Characterization of the Zinc Uptake Repressor (Zur) from Acinetobacter baumannii
Minyong Kim,
My Tra Le,
Lixin Fan
et al.
Abstract:Bacterial cells tightly regulate the intracellular concentrations of essential transition metal ions by deploying a panel of metal-regulated transcriptional repressors and activators that bind to operator-promoter regions upstream of regulated genes. Like other zinc uptake regulator (Zur) proteins, Acinetobacter baumannii Zur represses transcription of its regulon when Zn II is replete and binds more weakly to DNA when Zn II is limiting. Previous studies established that Zur proteins are homodimeric and harbor… Show more
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