Nuclear fission of heavy (actinide) nuclei results predominantly in asymmetric mass-splits. 1 Without quantum shells, which can give extra binding energy to these mass-asymmetric shapes, the nuclei would fission symmetrically. The strongest shell effects are in spherical nuclei, so naturally the spherical "doubly-magic" 132 Sn nucleus (Z = 50 protons), was expected to play a major role. However, a systematic study of fission has shown that the heavy fragments are distributed around Z = 52 to 56, 2 indicating that 132 Sn is not the only driver. Reconciling the strong spherical shell effects at Z = 50 with the different Z values of fission fragments observed in nature has been a longstanding puzzle. 3 Here, we show that the final mass asymmetry of the fragments is also determined by the extra stability of octupole (pear-shaped) deformations which have been recently confirmed experimentally around 144 Ba (Z = 56), 4, 5 one of very few nuclei with shellstabilized octupole deformation. 6 Using a modern quantum many-body model of superfluid fission dynamics, 7 we found that heavy fission fragments are produced predominantly with 52 − 56 protons, associated with significant octupole deformation acquired on the way to fission. These octupole shapes favouring asymmetric fission are induced by deformed shells at Z = 52 and 56. In contrast, spherical "magic" nuclei are very resistant to octupole deformation, which hinders their production as fission fragments. These findings may explain surprising observations of asymmetric fission of lighter than lead nuclei. 8 Atomic nuclei are usually found in a minimum of energy "ground-state" which may be deformed due to quantum correlations. Elongation beyond the ground-state costs potential energy until a maximum is reached at the fission barrier. Increasing the elongation beyond the fission barrier decreases the potential energy and the system follows a fission valley in the "potential energy surface" until it breaks into two fragments (scission). In the absence of quantum shell effects, all heavy nuclei preferentially fission into two fragments of similar mass (mass-symmetric fission). However, quantum shells in the fissioning nucleus can result in several valleys to scission. These may be mass-symmetric or mass-asymmetric.Although recent progress has been made in describing fission fragment mass distributions with stochastic based approaches, 9, 10 theoretical description of the first stage of fis-