Characterization of the novel <i><scp>HLA‐A</scp>*68:280</i> allele by sequencing‐based typing

clature update (Marsh, 2022) and, following agreed policy, have been assigned official allele designations (Marsh et al., 2010). Full details of all sequences will be published in a forthcoming report.Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries.Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly.Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publica-tions that describe new HLA sequences is given in Table 3. An additional 295 alleles were recently published but have not been included in Table 3 due to space considerations (Turner et al., 2022). In addition, the sequence for the allele A*02:01:08 has been extended to become a new A*02 protein variant. The allele name A*02:01:08 has been abandoned and the sequence renamed A*02:1040. Furthermore, the sequence for the allele C*08:01:08 has been extended and shown to be a new silent variant of the C*08:22 protein group. The allele name C*08:01:08 has been abandoned and the sequence renamed C*08:22:02.All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IPD-IMGT/HLA Database using the sequence submission tool provided (Robinson et al., 2020). The IPD-IMGT/HLA Database may be accessed via www.ebi.ac.uk/ipd/imgt/hla.

show abstract

Nomenclature for factors of the HLA system, update January, February, and March 2022

Marsh

2022

HLA

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Characterization of the novel HLA‐A68:280* allele by sequencing‐based typing

Abstract: A single nucleotide change in exon 2 of HLA‐A68:01:02:02 results in the novel HLA‐A68:280 allele.

Cited by 3 publications

References 3 publications

Nomenclature for factors of the HLA system, update January, February and March 2022

Nomenclature for factors of the HLA system, update January, February and March 2022

Nomenclature for factors of the HLA system, update January, February and March 2022

Nomenclature for factors of the HLA system, update January, February, and March 2022

Contact Info

Product

Resources

About

Characterization of the novel HLA‐A*68:280 allele by sequencing‐based typing

Abstract: A single nucleotide change in exon 2 of HLA‐A*68:01:02:02 results in the novel HLA‐A*68:280 allele.

Cited by 3 publications

References 3 publications

Nomenclature for factors of the HLA system, update January, February and March 2022

Nomenclature for factors of the HLA system, update January, February and March 2022

Nomenclature for factors of the HLA system, update January, February and March 2022

Nomenclature for factors of the HLA system, update January, February, and March 2022

Contact Info

Product

Resources

About

Characterization of the novel HLA‐A68:280* allele by sequencing‐based typing

Abstract: A single nucleotide change in exon 2 of HLA‐A68:01:02:02 results in the novel HLA‐A68:280 allele.