Abstract:The fluidic parameters of the Intrector vitrectomy device measured in this study suggest that at comfortable sustainable syringe pull forces, vacuum levels and liquid aspiration rates are similar to some other commercially available systems and are likely safe.
“…Newer models have allowed for better visualization and more precise surgical maneuvers to be performed within the clinic or minor procedure room. While not a replacement for in-OR 3-port pars-plana vitrectomy, the potential of the office-based vitrector now seems expansive [3,4,10-12,14]. The incidence of reported complications and endophthalmitis following office-based vitrectomy remains largely unknown.…”
Section: Discussionmentioning
confidence: 99%
“…Those who had received a minimum of 2 months of omega-3 supplementation prior to intervention were compared to case-matched patients who had received no supplements. For cytokines levels and lipidomics profiling, all patients underwent a one-time vitreous biopsy where undiluted vitreous samples were collected at the time of anti-VEGF (bevacizumab 1.25 mg/0.05 ml) and dexamethasone injections using a portable office-based vitrectomy device (Retrector, Insight Instruments, Inc, Stuart, FL) [4,10-12]. Half of each vitreous sample was sent for cytokines and lipidomics analysis whereas the other half was sent along with conjunctival samples for microbial analysis.…”
BackgroundTo perform a microbiological contamination analysis of the vitreous during office-based micro-incision vitrectomy surgery (MIVS) assessing whether the bacteria detected correlated with patient's ocular conjunctival flora.MethodsThis is a prospective, interventional, nonrandomized case series of patients undergoing office-based MIVS, anti-VEGF, and dexamethasone intravitreal injections (triple therapy) for the treatment of wet age-related macular degeneration (AMD) and diabetic macular edema (DME).All patients were operated at a small procedure room in an ambulatory clinic of the Department of Ophthalmology, University of Montreal, Quebec, Canada. Conjunctival samples were done before placing the sclerotomies. The MIVS was done with a 23-gauge retractable vitrector, a 27-gauge infusion line, and a 29-gauge chandelier. Undiluted and diluted vitreous were collected for aerobic, anaerobic and fungal cultures. Outcomes measured were bacterial species identification within samples collected from the conjunctiva and the vitreous.ResultsThirty-seven patients (37 eyes) were recruited and completed over 17 months of follow-up. Twenty-eight had wet AMD and nine had DME. There were 13 men and 24 women, with a mean age of 78 years. Eighteen patients (46%) had culture positive conjunctival flora. Twenty-six bacterial colonies were tabulated in total from the conjunctival swabs. All bacteria detected were gram-positive bacteria (100%), most commonly: Staphylococcus epidermitis in 11 (42%) and Corynebacterium sp. in 6 (23%). Only 1/18 patients had more than 3 species isolated, 6/18 patients had 2 species and 11/18 patients had 1 species identified on the conjunctival swab. Only 1 of the 37 undiluted midvitreous samples was culture positive, equating to a contamination rate of 2.7%. None of the diluted vitreous samples were culture positive. All cultures were negative for fungus. No serious postoperative complications occurred, including bacterial endophthalmitis, choroidal detachment, and retinal detachment.ConclusionThis preliminary study of office-based MIVS gives us insights on the ocular surface microbial profile and vitreous contamination rate of performing such procedures outside the OR-controlled environment. Our initial results seem to indicate that there is little risk of bacterial translocation and contamination from the conjunctiva into the vitreous. Therefore, if endophthalmitis occurs post-operatively, the source may likely arise after the procedure. Larger studies are needed to confirm our data.
“…Newer models have allowed for better visualization and more precise surgical maneuvers to be performed within the clinic or minor procedure room. While not a replacement for in-OR 3-port pars-plana vitrectomy, the potential of the office-based vitrector now seems expansive [3,4,10-12,14]. The incidence of reported complications and endophthalmitis following office-based vitrectomy remains largely unknown.…”
Section: Discussionmentioning
confidence: 99%
“…Those who had received a minimum of 2 months of omega-3 supplementation prior to intervention were compared to case-matched patients who had received no supplements. For cytokines levels and lipidomics profiling, all patients underwent a one-time vitreous biopsy where undiluted vitreous samples were collected at the time of anti-VEGF (bevacizumab 1.25 mg/0.05 ml) and dexamethasone injections using a portable office-based vitrectomy device (Retrector, Insight Instruments, Inc, Stuart, FL) [4,10-12]. Half of each vitreous sample was sent for cytokines and lipidomics analysis whereas the other half was sent along with conjunctival samples for microbial analysis.…”
BackgroundTo perform a microbiological contamination analysis of the vitreous during office-based micro-incision vitrectomy surgery (MIVS) assessing whether the bacteria detected correlated with patient's ocular conjunctival flora.MethodsThis is a prospective, interventional, nonrandomized case series of patients undergoing office-based MIVS, anti-VEGF, and dexamethasone intravitreal injections (triple therapy) for the treatment of wet age-related macular degeneration (AMD) and diabetic macular edema (DME).All patients were operated at a small procedure room in an ambulatory clinic of the Department of Ophthalmology, University of Montreal, Quebec, Canada. Conjunctival samples were done before placing the sclerotomies. The MIVS was done with a 23-gauge retractable vitrector, a 27-gauge infusion line, and a 29-gauge chandelier. Undiluted and diluted vitreous were collected for aerobic, anaerobic and fungal cultures. Outcomes measured were bacterial species identification within samples collected from the conjunctiva and the vitreous.ResultsThirty-seven patients (37 eyes) were recruited and completed over 17 months of follow-up. Twenty-eight had wet AMD and nine had DME. There were 13 men and 24 women, with a mean age of 78 years. Eighteen patients (46%) had culture positive conjunctival flora. Twenty-six bacterial colonies were tabulated in total from the conjunctival swabs. All bacteria detected were gram-positive bacteria (100%), most commonly: Staphylococcus epidermitis in 11 (42%) and Corynebacterium sp. in 6 (23%). Only 1/18 patients had more than 3 species isolated, 6/18 patients had 2 species and 11/18 patients had 1 species identified on the conjunctival swab. Only 1 of the 37 undiluted midvitreous samples was culture positive, equating to a contamination rate of 2.7%. None of the diluted vitreous samples were culture positive. All cultures were negative for fungus. No serious postoperative complications occurred, including bacterial endophthalmitis, choroidal detachment, and retinal detachment.ConclusionThis preliminary study of office-based MIVS gives us insights on the ocular surface microbial profile and vitreous contamination rate of performing such procedures outside the OR-controlled environment. Our initial results seem to indicate that there is little risk of bacterial translocation and contamination from the conjunctiva into the vitreous. Therefore, if endophthalmitis occurs post-operatively, the source may likely arise after the procedure. Larger studies are needed to confirm our data.
“…Cihazda kesicinin görev döngüsü açık, kapalı veya nötral olarak değiştirilerek farklı kesi hızları ve vakum değerlerinde istenen vitreus aspirasyon akım hızı elde edilebilmektedir. 12,14 VersaVIT 2.0, aktif görev döngüsü kontrolü ile birlikte yüksek hızda kesim sağlamasıyla birinci nesil VersaVIT sistemine göre daha üstün özelliklere sahiptir. Hem yüksek hızlı kesme hem de görev döngüsü kontrolü sayesinde daha etkin bir kor vitrektomi ve aynı zamanda daha güvenli bir vitreus tabanı temizliği mümkündür.…”
The Synergetics VersaVIT 2.0 (Bausch and Lomb) unit has been introduced as a portable system that can be easily moved from the operating room to the office environment and can also run on battery power. Although the VersaVIT 2.0 system is frequently preferred for uncomplicated and long-lasting cases such as vitreous hemorrhage, vitreous condensation, epiretinal membrane, and macular hole, especially in private practice and outpatient surgery centers, complicated vitreoretinal surgeries can also be performed with the system.
The installation of the system is provided in a very short time, such as 10 seconds, and due to its simplicity of use, it is possible to perform surgery with personnel who do not have vitrectomy training. VersaVIT 2.0® is a unique portative vitrectomy system that has a cut rate of 6000 cpm. The entire unit is quite light. It can run on electric current power or up to 60 minutes on a rechargeable internal battery. This system includes the entire vitreoretinal product line, including endolaser probes, endoilluminators, chandeliers, and packs. It allows working with 23, 25, and 27g trocar systems and product bases. Illuminated options of laser probe, vitrector, and infusion cannula are available. Endoilluminators have options that provide both focal, Middlefield, and widefield panoramic lighting. Unlike the first model, VersaVIT 2.0 also has the option of silicone injection and removal features. It has a new trocar system for faster and more practical application. Special trocars are available for pediatric cases. VersaVIT 2.0 is a vitrectomy machine that is portable due to its small size and is preferred in selected cases and also allows advanced vitreoretinal surgeries with its sufficient fluidity and good cutting properties.
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