Characterization of the dual regulation by a c-di-GMP riboswitch Bc1 with a long expression platform from
Bacillus thuringiensis
Lu Liu,
Dehua Luo,
Yongji Zhang
et al.
Abstract:A riboswitch generally regulates the expression of its downstream genes through conformational change in its expression platform (EP) upon ligand binding. The cyclic diguanosine monophosphate (c-di-GMP) class I riboswitch Bc1 is widespread and conserved among
Bacillus cereus
group species. In this study, we revealed that Bc1 has a long EP with two typical ρ-independent terminator sequences 28 bp apart. The upstream terminator T1 is dominant
in vitro
, whi… Show more
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