Characterization of the complete chloroplast genome of the prickly blue poppy <i>Meconopsis horridula</i> Hook. f. &amp; Thomson (Ranunculales: Papaveraceae)

Dan, Quehu; Li, Qien; Li, XianJia; Suonan, Renqian; Dongzhi, Duojie; Guo, Xiao

doi:10.1080/23802359.2021.1882902

Cited by 3 publications

(1 citation statement)

References 16 publications

(13 reference statements)

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“…The sequences used were: M. bella NC_080898 (unpublished), M. betonicifolia OK349678 (unpublished), M. henrici NC_050877 (Zhu and Zhang 2020 ), M. horridula NC_056967 (Dan et al. 2021 ), M. integrifolia NC_061607 (Li et al. 2020 ), M. paniculata OR521090 (unpublished), M. pinnatifolia OR521089 (unpublished), M. pseudohorridula ON756033 (unpublished), M. punicea NC_050878 (Zhu and Zhang 2020 ), M. quintuplinervia NC_056996 (Xu et al.…”

Section: Resultsmentioning

confidence: 99%

The complete chloroplast genome of Meconopsis torquata (Papaveraceae), a traditional Tibetan medicine

Zeng,

Xu,

Qiong

et al. 2024

Mitochondrial DNA Part B

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Section: Resultsmentioning

confidence: 99%

The complete chloroplast genome of Meconopsis torquata (Papaveraceae), a traditional Tibetan medicine

Zeng,

Xu,

Qiong

et al. 2024

Mitochondrial DNA Part B

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Effect of PI3K/AKT/mTOR signaling pathway-based clustered nursing care combined with papaverine injection on vascular inflammation and vascular crisis after replantation of severed fingers

Wang,

Xiao,

et al. 2023

Mol Cell Biochem

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This research aimed to investigate the effect of PI3K (phosphatidylinositol 3-kinase)/AKT (protein kinase B)/mTOR (mammalian target protein of rapamycin) signaling pathway-based clustering care combined with papaverine injection on vascular inflammation and vascular crisis after finger amputation and replantation. 100 patients admitted in General Hospital of Ningxia Medical University from April 2022 to December 2022 for replantation of severed fingers were selected and divided into a control group (n = 50) and an observation group (n = 50) using the randomized grouping principle. The control group received a papaverine injection and general nursing care, the observation group received a papaverine injection and clustered care. The pain score; constipation incidence; replantation finger survival rate; physician, nurse, and patient satisfaction; serum inflammatory factors; vascular crisis parameters; and occurrence of adverse reactions were compared between the two patient groups. Enzyme-linked immunosorbent assay was performed to detect PI3K, AKT, and mTOR protein concentrations in the venous blood of the two groups, and statistical analysis of the data was performed. On postoperative day 7, the pain score and incidence of constipation in the observation group were lower than those in the control group (P < 0.05); the survival rate of reimplanted fingers in the observation group was 88.00%, which was higher than that in the control group 80.00% (P < 0.05); the satisfaction of doctors, nurses, and patients in the observation group was higher than that in the control group; the concentrations of interleukin-1 (IL-1), tumor necrosis factor (TNF-α), blood flow resistance index (RI), and arterial pulsatility index (PI) in the observation group were lower than those in the control group, while the concentration of interleukin-10 (IL-10), vascular diameter, and Vm (mean blood flow velocity) were higher in the observation group than those in the control group; the differences were statistically significant (P < 0.05). The difference in the incidence of adverse reactions between the two groups was not statistically significant (P > 0.05). The concentrations of PI3K, AKT, and mTOR proteins in the observation group were higher than those in the control group (P < 0.05). The concentrations of PI3K, AKT, and mTOR proteins in the observation group were higher than those in the control group (P < 0.05). Overall, these findings suggest that clustered care combined with papaverine injection reduces vascular inflammatory symptoms and vascular crisis in the treatment of severed finger replantation through the PI3K/AKT/mTOR signaling pathway.

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Herbgenomics meets Papaveraceae: a promising -omics perspective on medicinal plant research

Kielich,

Mazur,

Musidlak

et al. 2023

Briefings in Functional Genomics

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Herbal medicines were widely used in ancient and modern societies as remedies for human ailments. Notably, the Papaveraceae family includes well-known species, such as Papaver somniferum and Chelidonium majus, which possess medicinal properties due to their latex content. Latex-bearing plants are a rich source of diverse bioactive compounds, with applications ranging from narcotics to analgesics and relaxants. With the advent of high-throughput technologies and advancements in sequencing tools, an opportunity exists to bridge the knowledge gap between the genetic information of herbs and the regulatory networks underlying their medicinal activities. This emerging discipline, known as herbgenomics, combines genomic information with other -omics studies to unravel the genetic foundations, including essential gene functions and secondary metabolite biosynthesis pathways. Furthermore, exploring the genomes of various medicinal plants enables the utilization of modern genetic manipulation techniques, such as Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR/Cas9) or RNA interference. This technological revolution has facilitated systematic studies of model herbs, targeted breeding of medicinal plants, the establishment of gene banks and the adoption of synthetic biology approaches. In this article, we provide a comprehensive overview of the recent advances in genomic, transcriptomic, proteomic and metabolomic research on species within the Papaveraceae family. Additionally, it briefly explores the potential applications and key opportunities offered by the -omics perspective in the pharmaceutical industry and the agrobiotechnology field.

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Characterization of the complete chloroplast genome of the prickly blue poppy Meconopsis horridula Hook. f. & Thomson (Ranunculales: Papaveraceae)

Cited by 3 publications

References 16 publications

The complete chloroplast genome of Meconopsis torquata (Papaveraceae), a traditional Tibetan medicine

The complete chloroplast genome of Meconopsis torquata (Papaveraceae), a traditional Tibetan medicine

Effect of PI3K/AKT/mTOR signaling pathway-based clustered nursing care combined with papaverine injection on vascular inflammation and vascular crisis after replantation of severed fingers

Herbgenomics meets Papaveraceae: a promising -omics perspective on medicinal plant research

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