Characterization of surfactant vesicles as membrane mimetic agents. 2. Temperature-dependent changes of the turbidity, viscosity, fluorescence polarization of 2-methylanthracene, and positron annihilation in sonicated dioctadecyldimethylammonium chloride

Synthetic Bilayer Fragments for Solubilization of Amphotericin B

“…Lipids were dispersed in water using procedures that yield vesicles and/or bilayer fragments. DODAB or DHP were dispersed by sonication with tip (30,31), ethanolic injection (32,33), or chloroform vaporization (34,35); ASO, by vortexing (36,37); PC, by ethanolic injection (32,33). DODAB was determined by microtitration (38) and other lipids, from inorganic phosphorus analysis (39).…”

Neisseria lactamicaantigens complexed with a novel cationic adjuvant

“…Administration of a single dose of the antigen was compared with two doses, and the results electrostatic repulsion of the molecules. [17][18][19] DDA-BF can be used as an adjuvant, and its main advantage is that DDA-BF requires a lipid concentration lower than the concentrations traditionally used in liposomal formulations. [20][21][22] Therefore, DDA-BF typically causes less toxicity.…”

Effect of Sonication on the Thermotropic Behavior of DODAB Vesicles Studied by Fluorescence Probe Solubilization

“…Vesicle properties, such as stability, permeability, melting temperature, degree of ionization and size, among others, depend on the chemical composition of the lipids ionic, strength, temperature, pH, and method of vesicle preparation [3][4][5][6][7][8][9][10]. It has been reported that sonicated aqueous dispersions of a DODAB consist of one population of bilayer fragments (R H = 8.5 nm) and another E. Feitosa (&) Physics Department, IBILCE/UNESP, Rua Cristovao Colombo 2265, São José do Rio Preto, SP 15054-000, Brazil e-mail: eloi@ibilce.unesp.br population of vesicles (R H = 22 nm) [9], while spontaneous DODAB aqueous dispersions contain two populations of vesicles with R H = 80 and 337 nm [10].…”