Characterization of Some Dermato-Cosmetic Preparations with Marine Lipids from Black Sea Wild Stingray

Abstract

The traditional knowledge about the therapeutic and nutritional value of fish has been unanimously recognized among the population since ancient times. So, thanks to the therapeutic virtues of these marine animals, it was possible to develop therapies for certain pathologies as well as the use of bioactive compounds as adjunctive therapies incorporated into the treatment regimen of patients. In the present study, stingray liver oil from wild species collected from the Romanian coast of the Black Sea was isolated and analyzed. Fatty acid analysis was performed by gas chromatography. The analysis of the distribution of fatty acids in the composition of stingray liver oil indicates a ratio of 3.68 of omega 3 fatty acids to omega 6, a ratio of 1.21 of polyunsaturated fatty acids to monounsaturated fatty acids, an iodine index of 111.85, and a total percentage of 79.24% of unsaturated fatty acids. Stingray liver oil was used to evaluate the healing action after preparing a fatty ointment. According to the experimental data, a complete regeneration capacity of the wounds was noted in 12 days without visible signs. Four emulgels with stingray liver oil were formulated and analyzed from a rheological and structural point of view in order to select the optimal composition, after which the anti-inflammatory effect on inflammation caused in laboratory rats was studied and an anti-inflammatory effect was found significant (a maximum inhibitory effect of 66.47% on the edemas induced by the 10% kaolin suspension and 65.64% on the edemas induced by the 6% dextran solution).

Advancements in Regenerative Hydrogels in Skin Wound Treatment: A Comprehensive Review

“…Traumatic injuries of any nature (mechanical, thermal, chemical, electrical) impose stress at the cellular level that can often unbalance the normal functioning of the biochemical and physiological healing processes of the skin lesions. Thus, a deficient healing process can lead to an abnormal closure of the wound, infection with pathogenic agents, and other aspects that attract problems of an esthetic nature but especially of a functional nature, because of the problem of affecting the activities of everyday life [372,373].…”

Development of New Dermato-Cosmetic Therapeutic Formulas with Extracts of Vinca minor L. Plants from the Dobrogea Region

“…To evaluate the anti-inflammatory action, two inflammatory agents were used that were administered intra-plantar by injection of 0.1 mL of 10% kaolin suspension and 0.2 mL of 6% dextran solution [50].…”