Characterization of skeletal muscle passive mechanical properties by novel micro-force sensor and tissue micro-dissection by femtosecond laser ablation

3D finite element models from serial section histology of skeletal muscle tissue – The role of micro-architecture on mechanical behaviour

“…In line with previous studies of our groups (Böl et al, 2014(Böl et al, , 2016Garcés-Schröder et al, 2018;Böl et al, 2019) histological investigations were performed on porcine biceps femoris muscle. A hind leg (𝑛 = 1) of a female domestic pig (Sus scrofa domestica) was obtained from a slaughterhouse immediately after animal sacrifice, and sample preparation started approx.…”

A genetic algorithm-based method for the mechanical characterization of biosamples using a MEMS microgripper: numerical simulations

“…Besides the studies on brain tissues and scaffolds, characterization and constitutive modeling of skeletal muscle (Marcucci et al, 2017;Garcés-Schröder et al, 2018), skin (Sherman et al, 2017;Hsu et al, 2018), lung (Freed and Einstein, 2012), blood vessels (Backman et al, 2017), pericardium (Murdock et al, 2018), articular cartilage (Marchi and Arruda, 2017), vocal fold (Erath et al, 2017), and cornea (Whitford et al, 2018) tissues have also been the subjects of extensive research efforts. It is worth noting that tissue stiffening is a hallmark of several disease states, including fibrosis and some types of cancers (Pogoda et al, 2014).…”

A Disposable Pneumatic Microgripper for Cell Manipulation with Image-Based Force Sensing

“…The measurement of the gripping force is another important aspect in a handling system for cell samples. Forces applied to very small samples of muscle tissue were measured for mechanical characterization using a force sensor featuring compliant, parallelogrammatic silicon structures [11]. The deflection of those structures was determined via piezo resistors that are doped into the silicon.…”

“…As with the actuators, a non-electric function is preferable for patch clamping. This means that common principles featuring Wheatstone bridges made of piezo resistors presented in various works [6,11,12,13] are not suitable. Gripping arms designed as flexible cantilevers are shown by Alogla et al [10].…”