Characterization of reactive impurities in methanol, ethanol, and 2-propanol by monitoring the activities of added ionic probes with ion selective electrodes

Deshmukh, B. K.; Coetzee, J. F.

doi:10.1021/ac00277a026

Cited by 14 publications

(18 citation statements)

References 3 publications

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“…We advocate the experimental protocol described here for the reasons indicated in the Introduction section and because it proved highly effective in detecting and determining previously unsuspected impurities, particularly amines, in reagent grade alcohols [1,17].…”

Section: Results and Mscusionmentioning

confidence: 99%

“…Fortunately, the concentrations of the majority of these impurities could be lowered to below lo-' or even M by careful fractionation, but even such low concentrations can be harmful in certain uses of the solvent, as described elsewhere [1,17]. In addition, an unidentified impurity with optical absorbance in the 240 to 340 nm region is present in the impure solvent [27].…”

Section: Gas Chromatography Of Propylene Carbonatementioning

confidence: 99%

“…. &, the change in potential caused by the ligand is given by Equation 1 [17]: (1) Here, S is the Nernstian slope, 59/11 mV/decade in ah,, and [L] is the concentration of free ligand. Representative calculated response curves are shown in Figure 6.…”

Section: Gamma-butyrolactonementioning

confidence: 99%

“…This is a pervasive problem in realizing the potential utility of relatively inert solvents, and it typically receives too little attention. We have discussed this issue elsewhere [1,8] [1,17], a modification of conventional potentiometric titration that we have termed the ''ion probe method' is much more effective than the conventional method at lower impurity concentrations in those cases when properly responding indicator electrodes for highly reactive reagents are available. In addition, the ion probe method provides information on the response of the electrodes over a wide concentration range (typically lo-' to loT2 M) of reagent in both unbuffered and buffered solutions.…”

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confidence: 99%

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Studies on the response of potentiometric sensors and the characterization of reactive impurities in propylene carbonate and gamma‐butyrolactone as solvents

et al. 1993

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This article deals with an experimental protocol developed to characterize reactive impurities that seriously compromise the utility of relatively inert solvents such as those discussed here. It was found that potentiometric sensors for hydrogen, silver(I), and copper(I1) ions give Nernstian response over a broad activity range in solutions of widely differing buffer capacity in y-butyrolactone (GBL), a promising but inadequately explored solvent for a variety of applications. Advantage was taken of the proper response of these sensors in applying the "ion probe method" described before to characterize impurities in both unpurified and purified y-butyrolactone on the basis of their reactivities rather than their concentrations alone. The same sensors were also used in conventional potentiometric titrations of impurities in propylene carbonate (PC), a solvent that has been extensively used in fundamental studies of solute-solvent interactions as well as in the construction of commercial lithium batteries. The results of the potentiometric studies served as a guide in the design of appropriate gas chromatographic measurements. Three impurities not reported before were found in a reagent grade propylene carbonate: triethylamine and chloride ion, both at concentrations above M, as well as 1,2-dibromopropane. The effectiveness of different purification procedures was studied.

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Section: Results and Mscusionmentioning

confidence: 99%

Section: Gas Chromatography Of Propylene Carbonatementioning

confidence: 99%

Section: Gamma-butyrolactonementioning

confidence: 99%

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confidence: 99%

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Studies on the response of potentiometric sensors and the characterization of reactive impurities in propylene carbonate and gamma‐butyrolactone as solvents

et al. 1993

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“…2,6). These impurities include tnimethylamine in methanol, triethylanine in ethanol, n-propylamine and pynidine in acetonitnile, and triethylamine in propylene carbonate.…”

Section: Applications To Characterization Of Reactive Impurities In Nmentioning

confidence: 99%

Current trends in electrochemical studies of nonaqueous solutions

Coetzee¹

1986

Pure and Applied Chemistry

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-Current trends in electrochemical studies of nonaqueous solutions are discussed with the emphasis on experimental approaches judged to be particularly promising for the future development of both fundamental and applied aspects of the field of solution chemistry. Topics include recent developments in the application of potentiometric sensors to nonaqueous solutions, the potentialities of such new materials as reactively sputtered iridium oxide as hydrogen ion sensors, and the demonstrated or potential advantages of microelectrodes with diameters less than approximately 20 urn in cyclic voltamnetry and a variety of other electrochenical techniques applicable to nonaqueous solutions. The extension of electrochemical measurements to nonpolar media is emphasized. Recent developments in certain other areas such as applications of solid electrolytes and chemically modified electrodes, and studies of interfaces between immiscible solvents, are briefly discussed.

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Solvent Effects on the AIBN Forced Degradation of Cumene: Implications for Forced Degradation Practices

Nelson

Thompson

Yao

et al. 2009

Journal of Pharmaceutical Sciences

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Characterization of reactive impurities in methanol, ethanol, and 2-propanol by monitoring the activities of added ionic probes with ion selective electrodes

Cited by 14 publications

References 3 publications

Studies on the response of potentiometric sensors and the characterization of reactive impurities in propylene carbonate and gamma‐butyrolactone as solvents

Studies on the response of potentiometric sensors and the characterization of reactive impurities in propylene carbonate and gamma‐butyrolactone as solvents

Current trends in electrochemical studies of nonaqueous solutions

Solvent Effects on the AIBN Forced Degradation of Cumene: Implications for Forced Degradation Practices

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