Characterization of Powder Components of Commercial Bone Cements.

Imai, Yohji; Ohyama, Atsushi

doi:10.4012/dmj.20.345

Cited by 5 publications

(4 citation statements)

References 5 publications

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“…7,8 In fact, such organic agents are loaded into commercially available acrylic cement 9 that secures the prosthesis to bone and teeth. Petroleumderived acrylic materials (e.g., polymethylmethacrylate) serve as a basal polymer in cement, 10 whereas current information on the safety and renewability of biobased polymers recommends them as replacements for petroleum-derived polymers.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Material chemists have also paid great attention to the contact-active antimicrobial activities of quaternary ammonium compounds, − as alternatives for silver composites employing time-limited antimicrobial performance. , In fact, such organic agents are loaded into commercially available acrylic cement that secures the prosthesis to bone and teeth. Petroleum-derived acrylic materials (e.g., polymethylmethacrylate) serve as a basal polymer in cement, whereas current information on the safety and renewability of biobased polymers recommends them as replacements for petroleum-derived polymers.…”

Section: Introductionmentioning

confidence: 99%

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Development of Antimicrobial Thermoplastic Material from Archaeal Poly-γ-l-Glutamate and Its Nanofabrication

Ashiuchi

Fukushima

Oya

et al. 2013

ACS Appl. Mater. Interfaces

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Here we describe a stoichiometric ion-complex of archaeal poly-γ-L-glutamate (L-PGA) and hexadecylpyridinium cation (HDP(+)), called PGAIC, which shows remarkable chemical resistance and potential as a novel functional thermoplastic. PGAIC films suppressed the proliferation of prokaryotic (Escherichia coli, Bacillus subtilis, Salmonella typhimurium, and Staphylococcus aureus) and eukaryotic (Saccharomyces cerevisiae) microorganisms. Moreover, its antifungal activity was demonstrated against a prevalent species of Candida (Candida albicans) and a filamentous fungus (Aspergillus niger). The minimal inhibitory concentrations were estimated as 0.25 mg mL(-1), and zones of growth inhibition appeared when PGAIC-coated polyethylene terephthalate (PET) films were placed in culture plates, whereas PET had very little effect on fungal growth. Soluble PGAIC thus shows promises as an antimicrobial and as a coating substrate. We also succeeded in synthesizing an L-PGA-based nanofiber using an ethanol solution of PGAIC.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Development of Antimicrobial Thermoplastic Material from Archaeal Poly-γ-l-Glutamate and Its Nanofabrication

Ashiuchi

Fukushima

Oya

et al. 2013

ACS Appl. Mater. Interfaces

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“…However, BPO + concentration calculated for Hi Fatigue ® was twice as high as expected (8.4:17 ± 2 mg/g), while Cemex ® Genta contained only half the amount of the expected BPO+ (30:15 ± 0.5 mg/g). Discrepancies between the values given by the manufacturers on the package and measured BPO content was already reported by Imai and Ohyama (2001). Remarkable is the good coincidence between measured concentrations and manufacturer declaration for products being established on the marked for a long time.…”

Section: Discussionmentioning

confidence: 82%

Is benzoyl peroxide detectable under physiological conditions in orthopaedic cement?

Steiner

Melanie

Goessler

et al. 2021

IJNBM

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Background: Until today, benzoyl peroxide (BPO) as a potential polymethyl methacrylate (PMMA) cement allergen is the subject of controversial discussion. Question/Purposes: Few cases have been reported in literature and ought to be seen critically. To address this issue, the present study aims to determine BPO and their degradation products biphenyl (BP) and benzoic acid (BA) within hardened cement as well as their elution from cement. Methods: Six ordinary cements characterised by different BPO: DmpT ratio were chosen for the study. Subsequently, cements were tested in-vitro under destructive, physiologic and non-physiologic conditions. Results: BPO was not detectable under destructive and physiological conditions. Cements with a N, N-Dimethyl-para-toluidine (DmpT) surplus contained lower BPO, BP and BA concentrations compared to cements with BPO surplus. Conclusions: Furthermore, the ratio of DmpT:BPO had an impact on the turnover of BPO and its degradation products. Clinical Relevance: Moreover, BPO and BP elution under physiological conditions was not detectable (<0.1 µg/mL in saline solution at a ratio of 1+9 cement to saline solution), calling into question whether BPO is relevant as PMMA cement allergen.

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“…ABCs are commercialized in two components, a solid phase containing the polymer (which is usually polymethylmethacrylate, PMMA, or a derived copolymer), benzoyl peroxide (BPO), as the polymerization reaction initiator [9][10][11][12], and a radiopacifier agent such as barium sulfate (BaSO 4 ) or zirconium dioxide (ZrO 2 ). The liquid phase is composed of a monomer (generally methyl methacrylate, MMA), N,N-Dimethyl-p-Toluidine (DMPT) as an activator for the formation of radicals [7,11], and hydroquinone as a stabilizer to room temperature [1,5].…”

Section: Introductionmentioning

confidence: 99%

Optimization of Mechanical and Setting Properties in Acrylic Bone Cements Added with Graphene Oxide

et al. 2021

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The extended use of acrylic bone cements (ABC) in orthopedics presents some disadvantages related to the generation of high temperatures during methyl methacrylate polymerization, thermal tissue necrosis, and low mechanical properties. Both weaknesses cause an increase in costs for the health system and a decrease in the patient’s quality of life due to the prosthesis’s loosening. Materials such as graphene oxide (GO) have a reinforcing effect on ABC’s mechanical and setting properties. This article shows for the first time the interactions present between the factors sonication time and GO percentage in the liquid phase, together with the percentage of benzoyl peroxide (BPO) in the solid phase, on the mechanical and setting properties established for cements in the ISO 5833-02 standard. Optimization of the factors using a completely randomized experimental design with a factorial structure resulted in selecting nine combinations that presented an increase in compression, flexion, and the setting time and decreased the maximum temperature reached during the polymerization. All of these characteristics are desirable for improving the clinical performance of cement. Those containing 0.3 wt.% of GO were highlighted from the selected formulations because all the possible combinations of the studied factors generate desirable properties for the ABC.

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Characterization of Powder Components of Commercial Bone Cements.

Cited by 5 publications

References 5 publications

Development of Antimicrobial Thermoplastic Material from Archaeal Poly-γ-l-Glutamate and Its Nanofabrication

Development of Antimicrobial Thermoplastic Material from Archaeal Poly-γ-l-Glutamate and Its Nanofabrication

Is benzoyl peroxide detectable under physiological conditions in orthopaedic cement?

Optimization of Mechanical and Setting Properties in Acrylic Bone Cements Added with Graphene Oxide

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