Characterization of Photo-Crosslinked Methacrylated Type I Collagen as a Platform to Investigate Lymphatic Endothelial Cell Response
Brian Ruliffson,
Stephen Larson,
Eleni Xhupi
et al.
Abstract:Despite chronic fibrosis and associated excess extracellular matrix (ECM) deposition and crosslinking occurring in many pathological conditions, few in vitro studies examine how fibrosis-induced ECM stiffening impacts lymphatic endothelial cells (LEC) behavior and subsequent new lymphatic vessel growth and function. This study examined the stiffening profile of PhotoCol®—commercially available methacrylated type I collagen—photo-crosslinked with photoinitiators Lithium phenyl-2,4,6… Show more
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