Characterization of pharyngeal peristaltic pressure variability during volitional swallowing in healthy individuals

Abstract

Deglutitive Pharyngeal peristalsis generates pressures with significant degree of site-related and inter-subject variability. This variability is not influenced by age, position and volume of swallowed fluid.

Involvement of hypoglossal and recurrent laryngeal nerves on swallowing pressure

“…1B). Consistent with this finding, pharyngeal peristalsis during volitional swallowing generated pressures with a significant degree of intersubject variability in healthy humans (1). Another study showed that there was greater pressure generated at anterior and posterior sites of the UES than at lateral sites (15).…”

Defining pharyngeal contractile integral during high-resolution manometry in neonates: a neuromotor marker of pharyngeal vigor

“…Recent studies in adults using HRM methods revealed that pharyngeal peristaltic function can be quantifiable across its whole length and also recognized age-related changes (20-24). Additionally, important pharyngeal function metrics such as pharyngeal contractile integral (PhCI = mean contractile amplitude >20 mmHg × contractile length × contractile duration) (21, 22, 24, 25), maximal pharyngeal contraction (P-Max), and regional differences have been described (20, 21, 26). However, systematic examination of these pharyngeal peristaltic motor functions has not been characterized in human neonates.…”

Swallow strength training exercise for elderly: A health maintenance need

“…The manometric probe and its associated computerized recording and analysis system (ManoScan and ManoView Systems; Given Imaging, Duluth, GA) stores pressure data from 36 pressure sensors (1 cm sensor spacing), displays the manometric information in topographic or line graph formats, and provides postacquisition analytic tools for parameterization of temporal and spatial pressure data. We used the pharyngeal contractile integral (a feature of the ManoScan measurement software) that overcomes the known inherent recording site‐specific variability as a measure of pharyngeal contractility. Subjects were verbally cued to perform, in randomized fashion, 5 swallows each of dry as well as 5 and 10 mL water slowly injected in the oral cavity by a syringe and swallowed as a single bolus.…”

“…High‐resolution manometry was analyzed for pharyngeal contractile integral (PhCI), a parameter derived from the ManoView analysis software. The PhCI was characterized by circumscribing a space‐time box in the topographic ManoView display to surround the pharyngeal deglutitive pressure recording with the upper margin of the box at the most proximal probe sensor before deglutition and the distal margin of the box at the predetermined upper margin of the UES high‐pressure zone at the time of return of the high‐pressure zone to its resting manometric profile …”