Characterization of Peste des Petits Ruminants Virus, Eritrea, 2002–2011

Cosseddu, Gian Mario; Pinoni, C.; Polci, Andrea; Sebhatu, Tesfaalem Tekleghiorghis; Lelli, Rossella; Monaco, Federica

doi:10.3201/eid1901.121072

Cited by 18 publications

(17 citation statements)

References 5 publications

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“…However, this was surprising, since at the date of sampling, in 1997 for Cameroon and in 2004 for Central Africa Republic (Kwiatek et al, 2007;Banyard et al, 2010), there is no know history of animal movement from Asia in these countries. Currently, in a large zone encompassing Sudan, Ethiopia, Somalia and Kenya, lineage IV is slowly replacing PPRV lineage III (Khalafalla et al, 2010;Kwiatek et al, 2011;Cosseddu et al, 2013;Maganga et al, 2013). In West Africa, a similar scenario has occurred with lineage II.…”

Section: Evolution and Phylogenymentioning

confidence: 82%

Evolutionary genetics underlying the spread of peste des petits ruminants virus

2014

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Section: Evolution and Phylogenymentioning

confidence: 82%

Evolutionary genetics underlying the spread of peste des petits ruminants virus

2014

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“…PPRV strains that were first identified in Africa belong to lineages I, II and III while viruses belonging to lineage IV, also referred to as the Asian lineage, have been found in Asia including the Middle and Near East (Banyard et al., ; Kwiatek et al., ). Since 2008, lineage IV viruses have been regularly reported in different African countries and appears to be becoming the predominant lineage in different areas of this continent (Kwiatek et al., ; Cosseddu et al., ; Maganga et al., ; Muniraju et al., ).…”

Section: Introductionmentioning

confidence: 99%

Peste Des Petits Ruminants in Benin: Persistence of a Single Virus Genotype in the Country for Over 42 Years

Adombi

Waqas

Dundon

et al. 2016

Transbound Emerg Dis

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Peste des petits ruminants (PPR) is a contagious and often fatal disease affecting sheep and goats. Currently, it is endemic in Africa, the Middle and Near East, the Indian subcontinent and China. Understanding the molecular epidemiology and evolution of PPR virus (PPRV) can assist in the control of the transboundary spread of this economically important disease. We isolated PPRV from pathological and swab samples collected 42 years apart (1969 and 2011) in Benin, West Africa, and sequenced the full genome of two isolates (Benin/B1/1969 and Benin/10/2011). Phylogenetic analysis showed that all of the characterized isolates clustered within viral lineage II and that the 2011 isolates fell into two distinct subgroups. Comparison of the full genome sequences revealed a 95.3% identity at the nucleotide level, while at the protein level, the matrix protein was the most conserved between the two viruses with an identity of 99.7% and only one amino acid substitution over the 42-year sampling period. An analysis of specific amino acid residues of known or putative function did not identify any significant changes between the two viruses. A molecular clock analysis of complete PPRV genomes revealed that the lineage II viruses sampled here arose in the early 1960s and that these viruses have likely persisted in Benin since this time.

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“…Recently, PPRV has been detected in areas where it is considered endemic and in neighboring areas where it previously has not been reported. The reporting of “first cases” in regions where PPRV has been considered endemic is of little surprise and perhaps represents increased interest both in agricultural practices and diagnostic capacity ( 1 – 3 ). Increased development of the small ruminant health sector, expanding small ruminant populations, increased trade movement, and rinderpest eradication might all have affected PPRV detection ( 4 ).…”

mentioning

confidence: 99%