“…The PPIase activity of cyclophilins, in general, is regulated in a redox-dependent or independent manner. Contrary to the E. coli cyclophilin PPIB, that is regulated by redox-independent mechanisms (Hayano et al, 1991;Kaur et al, 2015), the PPIase activity of AtCYP19-3 (ROC2), AtCYP20-3, SmCYPA, CsCYP and TaCYPA-1 is subject to redox regulation (Motohashi et al, 2003;Gourlay et al, 2007;Laxa et al, 2007;Campos et al, 2013;Kaur et al, 2015Kaur et al, , 2017. Furthermore, the redoxregulatory mechanisms observed in different cyclophilins are also distinct.…”