“…In some of these derivatives, paclitaxel is linked to macromolecules, such as poly(ethyleneglycol) [28,29,30,31,32,33,34,35,36,37,38,39,40,41,42], N -(2-hydroxypropyl)methacrylamide [39,43,44,45,46,47], carboxy-methyldextran [48], poly( l -glutamic acid) [49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74], peptides [75,76], proteins [77,78,79], dendrimers [37,42,80,81] and HA [82,83,84,85,86,87]. Joining a bioactive compound to a biocompatible polymer offers, in general, several advantages like better drug solubilization, stabili...…”