Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation

Nemenov, Michael I.; Alaverdyan, Harutyun; Burk, Carrie; Roles, Kristen; Frey, Karen; Yan, Yan; Kazinets, Gene; Haroutounian, Simon

doi:10.1016/j.jpain.2021.11.011

Cited by 3 publications

(2 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, it is noteworthy that only two investigations employed monofilament for the assessment [ 26 , 31 ], although sensitivity problems are common in CIPN. Concerning the sensory changes in CIPN, a publication from 2022 [ 36 ] noted that there are still no methods available for early detection or specific biomarkers. Finally, only one study collected variables from the person’s perspective, when currently [ 37 ] it is recommended to include the subjective experiences of people with the evaluation of clinical professionals.…”

Section: Discussionmentioning

confidence: 99%

Wellbeing and Complementary Therapies in Breast Cancer Peripheral Neuropathy Care: A Scoping Review Focused on Foot Health

Veiga-Seijo

Perez-Lopez

Fernandez-Lopez

et al. 2023

Cancers

View full text Add to dashboard Cite

Background: Chemotherapy-induced peripheral neuropathy is a multidimensional health problem. Up to now, little evidence has been found concerning its impact on quality of life and foot health. Evaluation tools and prevention and treatment strategies must be reported. This study aimed to map the literature on the impact of this side effect on the wellbeing and foot health of people with breast cancer and to describe their main assessment strategies and complementary therapies. Methods: A scoping review was carried out while following the PRISMA-ScR and Arksey and O’Malley guidelines. Different databases (Cochrane Plus, Scopus, Web of Science, and Pubmed) were used. A total of 221 results were identified. Sixteen articles were included. Results: The thematic analysis obtained the following categories: the impact of peripheral neuropathy on quality of life and foot health, complementary therapies as a path for new strategies, and the need for clinicians and researchers to get involved in researching this side effect. Conclusions: Peripheral neuropathy has a negative impact on people’s quality of life. Implications for foot health and maintaining an active and healthy lifestyle have not been previously reported. Complementary therapies are recommended by scientific evidence, highlighting exercise. However, there is a need to develop more research that will help to incorporate them into evidence-based practice.

show abstract

Section: Discussionmentioning

confidence: 99%

Wellbeing and Complementary Therapies in Breast Cancer Peripheral Neuropathy Care: A Scoping Review Focused on Foot Health

Veiga-Seijo

Perez-Lopez

Fernandez-Lopez

et al. 2023

Cancers

View full text Add to dashboard Cite

show abstract

“…Second, prolonged usage of the pin electrode (small nerve fibers) sometimes caused an unspecific, tingling, or burning feeling that would persist between stimulations. 22 This is believed to be caused by the activation of C-fibers (in contrast to the predominant activation of Aδ-fibers otherwise caused by the method), which could confuse the participants without sufficient instruction. Possible shunting of the electrical signal through the epidermis by means of hair fascicles is also something to consider when using the pin electrode (small fibers), although this would require an electrode placement directly on top of a hair fascicle or sweet duct.…”

Section: Discussionmentioning

confidence: 99%

Perception threshold tracking: validating a novel method for assessing function of large and small sensory nerve fibers in diabetic peripheral neuropathy with and without pain

Røikjer

Croosu

Frøkjær

et al. 2022

Pain

View full text Add to dashboard Cite

show abstract

Chemotherapy-induced peripheral neuropathy biomarkers: current updates, challenges, and potentials

Soejitno,

Widyadharma

2024

Egypt J Neurol Psychiatry Neurosurg

View full text Add to dashboard Cite

Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating condition of peripheral nerve because of chemotherapeutic agent exposure among cancer patients. Despite its relatively high prevalence, to date, there has been no specific or standardized diagnostic criteria for CIPN and establishing diagnosis can be burdensome with significant time and efforts. Therefore, there is a need for an accurate biomarker to aid in early and objective diagnosis of CIPN. Based on the relevant pathogenesis of CIPN, herein we discussed several potential biomarker candidates to be incorporated in the diagnosis of CIPN, ranging from bodily fluid-based biomarker such as neurotrophic factors and neurofilaments, genetic biomarker such as microRNAs, electrophysiologic biomarker such as quantitative sensory testing, and imaging biomarkers such as high-resolution ultrasound and magnetic resonance neurography. We also discussed the strengths and weaknesses of each biomarker type, and future directions to accelerate its translation into routine use in clinical practice.

show abstract

Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation

Cited by 3 publications

References 67 publications

Wellbeing and Complementary Therapies in Breast Cancer Peripheral Neuropathy Care: A Scoping Review Focused on Foot Health

Wellbeing and Complementary Therapies in Breast Cancer Peripheral Neuropathy Care: A Scoping Review Focused on Foot Health

Perception threshold tracking: validating a novel method for assessing function of large and small sensory nerve fibers in diabetic peripheral neuropathy with and without pain

Chemotherapy-induced peripheral neuropathy biomarkers: current updates, challenges, and potentials

Contact Info

Product

Resources

About