Characterization of oral lichen planus in a subset of patients: A single-center experience

Almazrooa, SoulafaA; Alhelo, AzzaF; Mansour, GhadaA; Alhamed, Sanaa Aidroos; Alfarabi, Sara; Akeel, SaraK; Alhindi, NadaA; Alsulaimani, Lujain; Alamri, ManalA; Mawardi, HaniH

doi:10.4103/sjos.sjoralsci_11_20

Cited by 1 publication

(3 citation statements)

References 32 publications

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“…However, the figures from the World Bank mirrored this difference by showing increased percentages of individuals aged 65 and above in these countries compared to that in Saudi Arabia [26]. Notably, the youngest age to receive the among the current study sample (22) was similar to what was found in other patient cohorts in Brazil [16], but higher than other studies reporting ages as young as 10 and 15 [4,23].…”

Section: Discussionsupporting

confidence: 74%

“…The mean age of patients presently (47) was relatively younger than that of other OLP patient cohorts in Saudi (48) [22], China and Thailand (50) [4,19], Brazil (54) [16], Czech Republic (55) [17] and Spain (56) [18]. However, the figures from the World Bank mirrored this difference by showing increased percentages of individuals aged 65 and above in these countries compared to that in Saudi Arabia [26].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, another KSA-based study focused on hepatitis C virus serology among patients with lichen planus in Jazan [5]. Of note, a recent study that assessed the characteristics of 50 patients with OLP noted higher female prevalence, around one-third of them with diabetes and hypertension, and 64% had no oral symptoms [22]. Nevertheless, the study was limited by not detailing the histological features and relatively low sample size.…”

Section: Introductionmentioning

confidence: 99%

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Clinicohistological Characteristics of Patients with Oral Lichenoid Mucositis: A Retrospective Study for Dental Hospital Records

Alsoghier,

AlMadan,

Alali

et al. 2023

JCM

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Oral lichenoid mucositis (OLM) of the oral mucosa is a histological diagnosis mainly characterised by a band of inflammatory infiltrate in lamina propria and basal cell degeneration. These features describe oral lichen planus or oral lichenoid reaction. However, it could be seen in oral dysplasia. The study aimed to assess the demographics and clinicohistological characteristics of patients with OLM and their relevance to dysplastic changes in the oral mucosa. This was a cross-sectional and retrospective study of archived and electronic records of individuals with histological confirmation of OLM at King Saud University Medical City, Saudi Arabia. The descriptive and correlation assessments were used to describe the demographics and clinicohistological characteristics and their associations, respectively [p < 0.05]. The analysis included 140 records of patients with histological confirmation of OLM with a mean age of 47 (±13), and 57% (n = 81) were females. Notably, 40% of patients had at least one medical condition, mainly diabetes mellitus, 74% were asymptomatic, and 52% had lesions in the buccal mucosa. Dysplasia was seen in 18 (12%) of the 140 reviewed records. Regarding the associations between study variables, dysplastic changes were associated with the male gender [p = 0.024] and were of no significance with increased age [p = 0.594]. Moreover, having oral symptoms was associated with older age [p < 0.001], medical history of diabetes [p = 0.0132] and hypertension [p < 0.001]. The present study findings could help indicate the individuals with histologically confirmed OLM who suffer the most from the clinical disease and have an increased risk of dysplastic changes. Therefore, symptomatic management and long-term follow-up can be planned accordingly.

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