Characterization of Molecular Chaperone GroEL as a Potential Virulence Factor in Cronobacter sakazakii
Dongdong Zhu,
Yufei Fan,
Xiaoyi Wang
et al.
Abstract:The molecular chaperone GroEL of C. sakazakii, a highly conserved protein encoded by the gene grol, has the basic function of responding to heat shock, thus enhancing the bacterium’s adaptation to dry and high-temperature environments, which poses a threat to food safety and human health. Our previous study demonstrated that GroEL was found in the bacterial membrane fraction and caused a strong immune response in C. sakazakii. In this study, we tried to elucidate the subcellular location and virulent effects o… Show more
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