Characterization of MDR and ESBL-producing E. coli strains from healthy swine herds of north-eastern India

Sanjukta, Rajkumari; SURMANI, H; Mandakini, Rajkumari; Milton, Arockiasamy Arun Prince; Das, Surojit; Puro, K.; Ghatak, Sandeep; Shakuntala, I.; Sen, Alaattin

doi:10.56093/ijans.v89i6.91104

Cited by 3 publications

(1 citation statement)

References 27 publications

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“…Antibiotic resistance is directly related to the decrease in number of effective antibiotics available for the treatment of bacterial infections (Dobiasova et al 2013;Conrad et al 2017). Resistance to 1 st to 4 th generation cephalosporins is due to the production of extended spectrum betalactamases (ESBL), inhibited by clavulanic acid, sulbactam and tazobactam (Sanjukta et al 2019;Raheel et al 2022). The ESBLs are plasmid-mediated enzymes which hydrolyze and inactivate a range of β-Lactam antibiotics including aztreonam, penicillin & broadspectrum cephalosporin (Al-Muharrmi et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Investigations into the Role of Zoo Animals in Transmitting the Extended Spectrum Beta Lactamases (ESBL) E. coli in the Environment

2023

Int J Vet Sci

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Extended-spectrum beta-lactamases producing E. coli (ESBL E. coli) have emerged as an important human and veterinary medicine issue. Zoo animals may act as a reservoir of ESBL E. coli responsible for transmission of ESBL E. coli to humans, animals, and the environment. A total of one hundred fecal samples were collected from zoo animals of two different zoos and analyzed for presence of ESBL E. coli. E. coli isolates (n=52) were recovered from 100 samples. The combination of CTX-M and TEM genes (32/52; 61.5%) was commonly observed in ESBL E. coli isolates followed by TEM (10/52; 19.2%) and CTX genes (5/52; 9.6%). Antimicrobial susceptibility profiling of ESBL E. coli isolates showed that 100% of the isolates were resistant to more than three antibiotics. The study indicated that zoo animals may act as reservoirs for transmission of multidrug resistant ESBL E. coli to humans, animals, and environment.

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Section: Introductionmentioning

confidence: 99%

Investigations into the Role of Zoo Animals in Transmitting the Extended Spectrum Beta Lactamases (ESBL) E. coli in the Environment

2023

Int J Vet Sci

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Extended-spectrum beta-lactamase (ESBL)-positive Escherichia coli presence in urban aquatic environments in Kanpur, India

Johnson

Ginn

Bivins

et al. 2020

Journal of Water and Health

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In India high rates of antibiotic consumption and poor sanitation infrastructure combine to pose a significant risk to the public through the environmental transmission of antimicrobial resistance (AMR). The WHO has declared Extended-spectrum beta-lactamase (ESBL)-positive Escherichia coli a key indicator for the surveillance of AMR worldwide. In the current study, we measured the prevalence of AMR bacteria in an urban aquatic environment in India by detecting metabolically active ESBL-positive E. coli. Water samples were collected in duplicate from 16 representative environmental water sources including open canals, drains, and rivers around Kanpur, Uttar Pradesh. We detected culturable E. coli in environmental water at 11 (69%) of the sites. Out of the 11 sites that were positive for culturable E. coli, ESBL-producing E. coli was observed at 7 (64%). The prevalence of ESBL-producing E. coli detected in the urban aquatic environment suggests a threat of AMR bacteria to this region.

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Seasonal effect on the prevalence of virulence genes of non-O157 Verotoxic E.coli serogroups in faeces of cattle calves

PARUL,

BIST,

SHARMA

et al. 2023

Indian J of Anim Sci

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Calves faecal samples (n=216) were investigated to observe the effect of seasons on the prevalence of serogroups and virulence genes of non-O157 VTEC. A total of 177 (81.94%) E. coli were isolated and 32 (14.81%) were identified as VTEC and serotyping resulted in 13 different non-O157 ‘O’ serogroups. The prevalence of serogroups and their virulence genes was found to be influenced by seasons and highest number were shed in summer (22.22%) followed by rainy (13.88%) and winter season (8.33%), respectively. A higher prevalence of O9 and O11 serogroups (25% each) was observed in summers. Molecular detection of virulence genes revealed the overall prevalence of vt1 to be 37.5%, vt2 43.8%, (vt1+vt2) 18.8%, eaeA 21.9% and hlyA 34.4% genes. Dominance of hlyA 50% was observed in summers, whereas vt1 and vt2 were more prevalent during rain (50% each). The study revealed the link between the occurrence of hlyA gene and O9, O11 serogroups in summers as both the serogroups were hlyA gene bearer. This association might be responsible for more VTEC outbreaks in summers. So, faecal contamination of raw milk seems to pose greater threat of non-O157 VTEC outbreak during hotter and humid months.

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Characterization of MDR and ESBL-producing E. coli strains from healthy swine herds of north-eastern India

Cited by 3 publications

References 27 publications

Investigations into the Role of Zoo Animals in Transmitting the Extended Spectrum Beta Lactamases (ESBL) E. coli in the Environment

Investigations into the Role of Zoo Animals in Transmitting the Extended Spectrum Beta Lactamases (ESBL) E. coli in the Environment

Extended-spectrum beta-lactamase (ESBL)-positive Escherichia coli presence in urban aquatic environments in Kanpur, India

Seasonal effect on the prevalence of virulence genes of non-O157 Verotoxic E.coli serogroups in faeces of cattle calves

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