Characterization of Knee Osteoarthritis in Latin America. A Comparative Analysis of Clinical and Health Care Utilization in Argentina, Brazil, and Mexico

Burgos‐Vargas, Rubén; Cardiel, Mario H.; Loyola‐Sánchez, Adalberto; Abreu, Mirhelen Mendes de; Pons-Éstel, Bernardo A; Rossignol, Michel; Avouac, Bernard; Ferraz, Marcos Bosi; Halhol, Hafid

doi:10.1016/j.reumae.2013.07.006

Cited by 4 publications

(7 citation statements)

References 47 publications

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“…Burgos-Vargas et al [7] observed a direct correlation between self-reported functionality and the presence of KOA in older women. They also demonstrated that 74% of individuals with KOA showed functional limitations.…”

Section: Discussionmentioning

confidence: 97%

“…In addition, there are divergences between radiographic changes and the symptoms shown by patients. It is important to highlight that the subjects in this study are older individuals, and only older women were assessed because the disease is most common in females [7,8].…”

Section: Discussionmentioning

confidence: 99%

“…It affects 85% of individuals over 75 years old [6]. It is more common in women [7,8] and the knee is one of the joints most affected by the disease [9].…”

Section: Introductionmentioning

confidence: 99%

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Influence of knee osteoarthritis on functional performance, quality of life and pain in older women

et al. 2020

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Introduction: Knee osteoarthritis (KOA) is a common degenerative disease in older people, causing pain, stiffness and dysfunction. Objective: To determine the influence of KOA on functional performance (FP), quality of life (QoL) and pain in older women. Method: This is a cross-sectional study, in which 50 older women diagnosed with KOA and 51 without KOA participated. Participants were assessed using FP tests: Sit-to-stand (STS); Gait speed test (GST); Timed Up and Go (TUG); 6-minute walk test (6 MWT) and the Berg Balance Scale (BBS). Pain was assessed by the visual analog scale (VAS); quality of life by applying the SF-36; and self-perception of the disease by using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results: No intergroup statistical differences were found in the BBS (p: 0.42), STS (p: 0.59) and 6MWT (p: 0.97). However, the KOA group showed slower GS (p < 0.00) and longer time in TUG (p < 0.00). They also presented higher pain levels (p < 0.01), worse perceived health status regarding pain, stiffness and physical function (WOMAC) (p < 0.01), as well as worse QoL indices in functional capacity, physical limitations, pain and overall health status (p < 0.010). Conclusion: The results of the study demonstrate that older women with KOA showed a decline in FP, QoL and higher pain levels.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

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Influence of knee osteoarthritis on functional performance, quality of life and pain in older women

et al. 2020

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“…Osteoarthritis (OA) is a disease entity that is characterized by alterations in the articular cartilage, subchondral bone, ligaments, capsule, and synovial membrane. In Latin America, according to the Community Oriented Program for the Control of Rheumatic Diseases (COPCORD), the prevalence of OA ranges from 2.3 to 20.4%, and the global burden of disease in individuals between 50 and 69 years is 679.55 years lived with disability per 100,000 habitants (http://www.healthdata.org) [1][2][3][4]. Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics are the predominant modality of OA treatments, which at long-term or high-dose use may cause significant side effects, such as gastrointestinal bleeding, nephrotoxicity, and cardiovascular disease.…”

Section: Introductionmentioning

confidence: 99%

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics are the predominant modality of OA treatments, which at long-term or high-dose use may cause significant side effects, such as gastrointestinal bleeding, nephrotoxicity, and cardiovascular disease. However, intra-articular (IA) therapies employing diverse active drugs, such as corticosteroids and viscosupplementation, are also used [3,4].…”

Section: Introductionmentioning

confidence: 99%

Long-Term Effectiveness of Polymerized-Type I Collagen Intra-Articular Injections in Patients with Symptomatic Knee Osteoarthritis: Clinical and Radiographic Evaluation in a Cohort Study

Borja-Flores¹,

Macías‐Hernández

Hernández-Molina

et al. 2020

Advances in Orthopedics

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Objective. Polymerized-type I collagen (polymerized-collagen) is a downregulator of inflammation and a tissue regenerator. The aim was to evaluate the effect of intra-articular injections (IAIs) of polymerized-collagen among patients with symptomatic knee osteoarthritis (OA) in delaying or preventing joint replacement surgery. Patients and Methods. This was a cohort study of 309 patients with knee OA. Patients with mild-to-moderate disease were treated weekly with IAIs of 2 mL of polymerized-collagen for six weeks (n = 309). Follow-up was for 6–60 months. The primary endpoints included the following determinations: (1) therapeutic effect; (2) survival from total knee replacement surgery (TKR); (3) Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and pain (visual analogue scale, VAS). Clinical improvement was defined as a decrease in pain exceeding 20 mm on the VAS and the achievement of at least 20% improvement from baseline with respect to the WOMAC score. Radiographic analysis was performed at baseline and 60 months. The joint space width in the medial, lateral, and patellofemoral compartments was calculated. Results. Patients who received IAIs of polymerized-collagen had a statistically significant improvement in the primary criteria (p<0.05). Kaplan–Meier survival analysis of the therapeutic effect demonstrated 98.8% survival at 60 months with TKR as the endpoint. There was no significant reduction in joint space in any compartment based on the analyzed radiographs. No serious adverse events were recorded. Conclusion. Polymerized-collagen increased the time to TKR by at least 60 months, modifying the disease course, improving functional disability, and decreasing pain.

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Incorporation of photobiomodulation therapy into a therapeutic exercise program for knee osteoarthritis: A placebo‐controlled, randomized, clinical trial

Gomes

Leal-Junior²,

Dibai‐Filho

et al. 2018

Lasers Surg Med

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Characterization of Knee Osteoarthritis in Latin America. A Comparative Analysis of Clinical and Health Care Utilization in Argentina, Brazil, and Mexico

Cited by 4 publications

References 47 publications

Influence of knee osteoarthritis on functional performance, quality of life and pain in older women

Influence of knee osteoarthritis on functional performance, quality of life and pain in older women

Long-Term Effectiveness of Polymerized-Type I Collagen Intra-Articular Injections in Patients with Symptomatic Knee Osteoarthritis: Clinical and Radiographic Evaluation in a Cohort Study

Incorporation of photobiomodulation therapy into a therapeutic exercise program for knee osteoarthritis: A placebo‐controlled, randomized, clinical trial

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