Characterization of Hyperintense Plaque With Noncontrast T1-Weighted Cardiac Magnetic Resonance Coronary Plaque Imaging

Kawasaki, Terukazu; Koga, Shoichi; Koga, Nobuhiko; Noguchi, Teruo; Tanaka, Hidenori; Koga, Hisashi; Serikawa, Takeshi; Orita, Yoshiya; Ikeda, Shinsuke; Mito, Taro; Goto, Yoshitaka; Shintani, Yoshiaki; Tanaka, Atsushi; Fukuyama, Takeshi

doi:10.1016/j.jcmg.2009.01.016

Cited by 123 publications

(88 citation statements)

References 29 publications

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“…MRI imaging studies have shown that this technique can identify the presence of thrombus and high-risk plaques [114,115]. T1-weighted imaging can also provide useful prognostic information: in a study that included 568 patients with suspected CAD, an increased coronary plaque intensity in T1-weigthed imaging was independent predictor of future adverse cardiovascular events at 55 months follow-up (hazard ratio: 3.96; 95% confidence interval: 1.92-8.17; P < 0.001); nevertheless, there is no data today about the efficacy of MRI in detecting lesions that are likely to progress and cause cardiovascular events [116].…”

Section: Magnetic Resonance Imagingmentioning

confidence: 99%

Invasive or non-invasive imaging for detecting high-risk coronary lesions?

Patel

Tarkin

Serruys

et al. 2017

Expert Review of Cardiovascular Therapy

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Introduction: Advances in our understanding about atherosclerotic evolution have enabled us to identify specific plaque characteristics that are associated with coronary plaque vulnerability and cardiovascular events. With constant improvements in signal and image processing an arsenal of invasive and non-invasive imaging modalities have been developed that are capable of identifying these features allowing in vivo assessment of plaque vulnerability. Areas covered: This review article presents the available and emerging imaging modalities introduced to assess plaque morphology and biology, describes the evidence from the first large scale studies that evaluated the efficacy of invasive and non-invasive imaging in detecting lesions that are likely to progress and cause cardiovascular events and discusses the potential implications of the in vivo assessment of coronary artery pathology in the clinical setting. Expert commentary: Invasive imaging, with its high resolution, and in particular hybrid intravascular imaging appears as the ideal approach to study the mechanisms regulating atherosclerotic disease progression; whereas non-invasive imaging is expected to enable complete assessment of coronary tree pathology, detection of high-risk lesions, more accurate risk stratification and thus to allow a personalized treatment of vulnerable patients. ARTICLE HISTORY

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Section: Magnetic Resonance Imagingmentioning

confidence: 99%

Invasive or non-invasive imaging for detecting high-risk coronary lesions?

Patel

Tarkin

Serruys

et al. 2017

Expert Review of Cardiovascular Therapy

View full text Add to dashboard Cite

show abstract

“…In addition, noncontrast, TIW CMR was able to directly visualize thrombus in acute myocardial infarction and to detect the presence of coronary high-intensity plaques (HIPs), which correspond to positive remodeling and low-density plaques on CT [76,77]. Noguchi et al [78] took a further step by demonstrating that HIPs identified by non-contrast T1W MRI were significantly associated with coronary events.…”

Section: Coronary Artery Wall Imagingmentioning

confidence: 99%

Cardiac MR Assessment of Coronary Arteries

Hamdy

Ishida

Sakuma

2017

Cardiovasc Imaging Asia

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Imaging of coronary arteries with magnetic resonance has undergone undeniable progress during the past two decades. Although coronary computed tomography angiography detects coronary artery disease (CAD) with excellent diagnostic accuracy, the inevitable exposure to ionizing radiation and iodinated contrast administration make it less appealing in certain patient populations. Coronary magnetic resonance angiography (MRA) is now performed mostly as a whole heart, free breathing, three-dimensional study. Several factors influence quality and speed of the scan, including use of the appropriate pulse sequence according to the strength of the magnetic field, cardiac and respiratory gating, preparation pulses, multi-channel cardiac coils, parallel imaging, and contrast material injection. The use of coronary MRA is well established in coronary artery anomalies and aneurysms. While diagnostic performance has also improved markedly for the detection of CAD, coronary MRA is not yet a routine clinical study. However, coronary MRA is expected to be play a major role in the near future due to continuous research and technical achievements.

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“…[59][60][61][62][63] HIP was defined as plaque with higher plaque to myocardium signal intensity ratio (PMR), 59) which was calculated as the signal intensity of the cor- …”

Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Coronary Paque Imaging by Coronary Angioscopy-Comparison with the Other Modalities-

2017

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IntroductionFor more than decades, conventional invasive coronary angiography has been the gold standard for the diagnosis of coronary artery disease and clinical decision making for percutaneous coronary intervention (PCI) Coronary AngioscopyCoronary angioscopy enables direct visualization of internal surface of a vessel and provides the detail information of various plaque morphology or thrombus formation. 3,4) Coronary plaques are assessed based on the surface color and characteristics.Plaque color is classified as white, light yellow, yellow (medium yellow) or intensive yellow (dark yellow) 4,5) (Fig. 1A). Yellow plaques of higher color grade is strongly related with the positive remodeling, thrombus formation and thin-cap fibroatheroma (TCFA) and considered high-risk plaque, 5-8) whereas white plaques correlate fibrous plaque or pathological intimal thickening and is considered as stable plaque. 9) Coronary angioscopy also has the ability to visualize intraluminal thrombus for high sensitivity and specificity, 10) and angioscopic thrombus is classified as red, white or mixed thrombus 11) (Fig. 1B). Furthermore this modality allows evaluation of neointimal coverage (NIC) after stent implantation and NIC was classified into 3 or 4 grades 12,13) (Fig. 1C). In particular coronary angioscopy was the first imaging modality that enabled direct visualization of neoatherosclerosis after drug-eluting stent (DES) implantation. 14)Coronary Paque Imaging by Coronary Angioscopy Comparison with the Other ModalitiesHiroaki Watabe, MD, PhD, * Akira Sato, MD, and Kazutaka Aonuma, MD, PhD.Cardiovascular Division, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, JapanThe recent improvement of technical aspects of multimodality coronary imaging allow not only assessment of the degree of vessel luminal narrowing but also evaluation of the plaque characteristics and the useful prognostic information and accurate risk stratification. Among them, coronary angioscopy is the coronary imaging modality that enables direct visualization of internal surface of a vessel. Moreover it provides the detail information of plaque morphology, thrombus formation and neointimal coverage (NIC) after stent implantation. A lot of previous studies have shown that coronary angioscopy enabled not only the detection of vulnerable plaque but also prediction of cardiovascular events and percutaneous coronary intervention related complications. In this review, we discuss the role of coronary angioscopy for coronary plaque imaging, including in a comparison with other currently available imaging modalities used to examine atherosclerotic plaque.Key words: coronary angioscopy, vulnerable plaque, coronary imaging NIC at 1 year after 2nd-generation DES implantation was more homogeneous with white and less thrombus than that after 1st-generation DES. 13) Another study showed in-stent yellow plaque at 1 year after DES implantation was associated with cardiovascular event. 15)According to the reports of histopathologic validation of coronary angios...

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Characterization of Hyperintense Plaque With Noncontrast T1-Weighted Cardiac Magnetic Resonance Coronary Plaque Imaging

Cited by 123 publications

References 29 publications

Invasive or non-invasive imaging for detecting high-risk coronary lesions?

Invasive or non-invasive imaging for detecting high-risk coronary lesions?

Cardiac MR Assessment of Coronary Arteries

Coronary Paque Imaging by Coronary Angioscopy-Comparison with the Other Modalities-

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