Characterization of human Ccser2 as a protein tracking the plus-ends of microtubules
Yuko Shirai,
Tomohiro Okuda,
Kenzi Oshima
et al.
Abstract:Objective
Microtubules, which are closely related to cell proliferation, have been the promising therapeutic target of cancer. Therefore, it is necessary to understand the intracellular control mechanisms of microtubules, the whole picture of which is still unclear though. Intracellular dynamics of microtubules are regulated by various microtubule-associated proteins, one group of which is microtubule plus-end-tracking proteins (+ TIPs), localizing to the extending tips of microtubules. Here, w… Show more
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