Characterization of Human B Cell Hematological Malignancies Using Protein-Based Approaches
Cristina Jiménez,
Alba Garrote-de-Barros,
Carlos López-Portugués
et al.
Abstract:The maturation of B cells is a complex, multi-step process. During B cell differentiation, errors can occur, leading to the emergence of aberrant versions of B cells that, finally, constitute a malignant tumor. These B cell malignancies are classified into three main groups: leukemias, myelomas, and lymphomas, the latter being the most heterogeneous type. Since their discovery, multiple biological studies have been performed to characterize these diseases, aiming to define their specific features and determine… Show more
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