Characterization of freeze-dried oxidized human red blood cells for pre-transfusion testing by synchrotron FTIR microspectroscopy live-cell analysis

Veetil, Thulya Chakkumpulakkal puthan; Alves, Diana; Vongsvivut, Jitraporn; Wood, Bayden Robert; Garnier, Gil

doi:10.1039/d2an02001g

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Current Defects and Prospects1

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2023

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Cited by 2 publications

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“…The technology of RBCs preservation is also constantly advancing. Trehalose [ 173 ], pre-freeze oxidation [ 174 ], and liposome [ 175 ] have been determined to have a good effect on freeze drying of RBCs. However, the problem of potential hemolytic and thrombus risks also needs to be addressed before clinical application.…”

Section: Current Defects and Prospectsmentioning

confidence: 99%

Red blood cells: a potential delivery system

Chen,

Leng,

et al. 2023

J Nanobiotechnol

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Red blood cells (RBCs) are the most abundant cells in the body, possessing unique biological and physical properties. RBCs have demonstrated outstanding potential as delivery vehicles due to their low immunogenicity, long-circulating cycle, and immune characteristics, exhibiting delivery abilities. There have been several developments in understanding the delivery system of RBCs and their derivatives, and they have been applied in various aspects of biomedicine. This article compared the various physiological and physical characteristics of RBCs, analyzed their potential advantages in delivery systems, and summarized their existing practices in biomedicine. Graphical Abstract

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Section: Current Defects and Prospectsmentioning

confidence: 99%