Characterization of endo-metabolome exhibiting antimicrobial and antioxidant activities from endophytic fungus Cercospora sp. PM018

Mookherjee, Abhirup; Kutty, Nithya N.; Mitra, Adinpunya; Maiti, Mrinal K.

doi:10.1016/j.sajb.2020.01.040

Cited by 18 publications

(8 citation statements)

References 33 publications

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“…Menurut Mookherjeea et al (2020) Cercospora dapat berpotensi sebagai penghasil antimikroba dan antioksidan. Sedangkan Alternaria menghasilkan senyawa Altersolanol yang memiliki aktivitas antiangiogenesis (Triastuti, 2020)…”

Section: Hasilunclassified

ISOLASI DAN IDENTIFIKASI JAMUR ENDOFIT PADA TANAMAN STROBERI (Fragaria × ananassa Duch. ‘Rosalinda’) DI DESA CANDIKUNING KABUPATEN TABANAN, BALI

Meniwati,

Darmadi,

Hardini

2024

SIMBIOSIS

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Strawberries (Fragaria × ananassa Duch.) are subtropical plants well adapted to Indonesia’s highlands. Strawberries cultivated in Candikuning Village, Tabanan Regency, Bali are Fragaria × ananassa Duch. 'Rosalinda'. The fruit is widely used because it produces bioactive compounds. Bioactive compounds can also be obtained from endophytic fungi that live in host tissues. The study aimsed to identify the genus of endophytic fungi on the leaves and petioles of strawberries and to find out the benefits of the endophytic fungi found (literature review). This study used a descriptive method, which was carried out from December 2022 to February 2023. The stages in this study were the isolation of endophytic fungi, purification, and macroscopic and microscopic identification. There were 10 isolates of endophytic fungi isolated from leaves and petioles. Nine isolates were identified Aspergillus, Cercospora, Alternaria, Geotrichum, Penicillium, Cladosporium, Cylindrocladium, Cunninghamella, and Phytophthora. One isolate was not identified (mycelia sterile). These endophytic fungi are useful as biological controllers against plant pathogens, medicinal ingredients, and insecticides. Keywords: Candikuning, endophytic fungi, identification, isolation, strawberries

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Section: Hasilunclassified

ISOLASI DAN IDENTIFIKASI JAMUR ENDOFIT PADA TANAMAN STROBERI (Fragaria × ananassa Duch. ‘Rosalinda’) DI DESA CANDIKUNING KABUPATEN TABANAN, BALI

Meniwati,

Darmadi,

Hardini

2024

SIMBIOSIS

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“…Endophytic fungus Cercospora sp. isolated from Aerva javanica (an Indian indigenous medicinal plant) was proven to possess diverse bioactive potential (Mookherjee et al, 2020). The mechanism of growth inhibition of pathogens by endophytes may be due to competition for nutrition and space.…”

Section: Pathogenicity Of Isolates Tested and Antagonism Of The Endop...mentioning

confidence: 99%

Bioactivity of Some Endophytic Fungi from Cameroonian Medicinal Plants against Verticillium albo-atrum, Rhizoctonia carotae and Phytophthora megakarya

Djeugap,

Mbatkam,

Kouam

et al. 2024

Int. J. Phytopathol.

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Endophytic fungi (EFs) are beneficial microorganisms which grow in living plant tissues without causing any disease to their hosts. Most of them have antifungal properties. EFs of three herbaceous plants namely Lantana camara, Emilia coccinae and Bryophyllum pinnatum were isolated by using potato dextrose agar medium (PDA) and screened for their antifungal activity on the double direct confrontation (DDC) test on PDA. The growth diameter of pathogenic fungi with or without endophyte was measured weekly. Then, fourteen days after the DDC test, fungicidal or fungistatic activity of the EFs was assessed on the pathogens’ growth. Finally, EFs that strongly inhibited pathogens’ growth were submitted to the morphological characterization on PDA, Malt Extract Agar (MEA) and Sabouraud Dextrose Agar (SDA) media at three pH levels (5.2, 7 and 9). Results showed that eight EFs genera are associated with these herbaceous medicinal plants with diverse antifungal activities. EFs that significantly (p 0.05) inhibited the growth of the three pathogenic fungi were: Trichoderma harzianum (66%), Cercospora sp (58%) and Aspergillus sp (49%), 7 days after the DDC test. Endophytes T. harzianum and Cercospora sp were fungicidal on the three pathogens while Aspergillus sp was fungicidal on V. albo-atrum and R. carotae. There was a high morphological variability (colour, texture and pigments produced by EFs on culture media), and variability in their daily growth diameter and sporulation among EFs from one medium to another and from one pH level to another. This study suggests that T. harzianum and Cercospora sp endophytes possess the high antagonistic activity and can be used as an alternative to synthetic chemicals that control plant diseases

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“…Most of the active compounds isolated from endophytic fungi have antibacterial activity, and mycelium and fermentation liquid extracts can produce certain inhibitory activity against plant, animal and human pathogens ( Charria-Girón et al, 2021 ; Gu et al, 2022 ). Some secondary metabolites of endophytic fungi have good antibacterial activity and have been studied for the development of new drugs ( Atiphasaworn et al, 2017 ; Mookherjee et al, 2020 ; Muthukrishnan et al, 2022 ; Wen et al, 2022 ). The endophytic fungi isolated from most plants, especially medicinal plants, showed excellent antioxidant activity.…”

Section: Introductionmentioning

confidence: 99%

Diversity, chemical constituents and biological activities of endophytic fungi from Alisma orientale (Sam.) Juzep.

Shen

Zhao²,

Cheng

et al. 2023

Front. Microbiol.

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The dried tuber of Alisma orientale (Sam.) Juzep. (AOJ) is a traditional Chinese medicine with high medicinal value. The endophytic fungi of medicinal plants are a treasure house of natural compounds. However, there is a lack of research on the diversity and biological activity of endophytic fungi of AOJ. In this study, high-throughput sequencing technology was used to study the diversity of endophytic fungi in the roots and stems of AOJ, and endophytic fungi with a high output of phenols and flavonoids were screened by chromogenic reaction, and the antioxidant and antibacterial activities and chemical constituents of crude extracts of their fermentation broth were studied. A total of 3,426 amplicon sequence variants (ASVs) belonging to 9 phyla, 27 classes, 64 orders, 152 families, and 277 genera were identified from AOJ. There were significant differences in the endophytic fungal communities of AOJ roots and stems, as well as in the endophytic fungal communities of triangular AOJ and circular AOJ. In addition, 31 strains of endophytic fungi were isolated from AOJ, of which 6 strains had good antioxidant and antibacterial activities. The crude extract of YG-2 had the strongest free radical scavenging ability and bacteriostatic ability, and its IC50DPPH, IC50ABTS, and IC50⋅OH values were 0.009 ± 0.000 mg/mL, 0.023 ± 0.002 mg/mL, and 0.081 ± 0.006 mg/mL, respectively. The results of LC-MS showed that the main component of the crude extract of YG-2 was caffeic acid (10.12 μmol/g). Overall, the results of this study preliminarily elucidated the diversity and community composition of endophytic fungi of AOJ, indicating that AOJ endophytic fungi have abundant secondary metabolites and good antioxidant and antibacterial activities. This study provides an important reference for further research, development and utilization of AOJ endophytic fungi and a theoretical basis for the further development of the endophytic fungus YG-2 (Chaetomium globosum) as a source of antioxidants.

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Characterization of endo-metabolome exhibiting antimicrobial and antioxidant activities from endophytic fungus Cercospora sp. PM018

Cited by 18 publications

References 33 publications

ISOLASI DAN IDENTIFIKASI JAMUR ENDOFIT PADA TANAMAN STROBERI (Fragaria × ananassa Duch. ‘Rosalinda’) DI DESA CANDIKUNING KABUPATEN TABANAN, BALI

ISOLASI DAN IDENTIFIKASI JAMUR ENDOFIT PADA TANAMAN STROBERI (Fragaria × ananassa Duch. ‘Rosalinda’) DI DESA CANDIKUNING KABUPATEN TABANAN, BALI

Bioactivity of Some Endophytic Fungi from Cameroonian Medicinal Plants against Verticillium albo-atrum, Rhizoctonia carotae and Phytophthora megakarya

Diversity, chemical constituents and biological activities of endophytic fungi from Alisma orientale (Sam.) Juzep.

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