Characterization of chitosan composites with synthetic polymers and inorganic additives

Lewandowska, Katarzyna

doi:10.1016/j.ijbiomac.2015.08.003

Cited by 33 publications

(18 citation statements)

References 63 publications

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“…The mixture of poly(vinyl alcohol) with chitosan at a mass ratio of 50:50 (PVA:Ch-0) was characterized by lower values of mechanical properties in comparison with pure PVA. This is in accordance with the literature, where materials based on poly(vinyl alcohol) and chitosan have been described [55,56,61]. As described by other authors [55,56,61], the tensile strength of chitosan and PVA-chitosan blends is significantly lower than in the case of pure PVA.…”

Section: Mechanical Testingsupporting

confidence: 92%

“…This is in accordance with the literature, where materials based on poly(vinyl alcohol) and chitosan have been described [55,56,61]. As described by other authors [55,56,61], the tensile strength of chitosan and PVA-chitosan blends is significantly lower than in the case of pure PVA. The results of mechanical testing obtained by us and other researchers strongly indicate lower elongation at break, tensile stress, and Young's modulus values of neat chitosan, in comparison to PVA.…”

Section: Mechanical Testingsupporting

confidence: 92%

“…In the case of the PVA-0 samples, the first stage of decomposition was associated with moisture vaporization (80-150 • C). According to the literature [55,56], the second stage is connected with dehydration related to the formation of volatile products. In the last stage (at about 449 • C), further degradation occurs where carbon and hydrocarbons are produced.…”

Section: Thermal Propertiesmentioning

confidence: 99%

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Antibacterial Films Based on PVA and PVA–Chitosan Modified with Poly(Hexamethylene Guanidine)

et al. 2019

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In this study, thin, polymeric films consisting of poly(vinyl alcohol) (PVA) and chitosan (Ch) with the addition of poly(hexamethylene guanidine) (PHMG) were successfully prepared. The obtained materials were analyzed to determine their physicochemical and biocidal properties. In order to confirm the structure of PHMG, nuclear magnetic resonance spectroscopy (1H NMR) was applied, while in the case of the obtained films, attenuated total reflectance infrared spectroscopy with Fourier transform (FTIR-ATR) was used. The surface morphology of the polymer films was evaluated based on atomic force microscopy. Furthermore, the mechanical properties, color changes, and thermal stability of the obtained materials were determined. Microbiological tests were performed to evaluate the biocidal properties of the new materials with and without the addition of PHMG. These analyses confirmed the biocidal potential of films modified by PHMG and allowed for comparisons of their physicochemical properties with the properties of native films. In summary, films consisting of PVA and PHMG displayed higher antimicrobial potentials against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria in comparison to PVA:Ch-based films with the addition of PHMG.

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Section: Mechanical Testingsupporting

confidence: 92%

Section: Mechanical Testingsupporting

confidence: 92%

Section: Thermal Propertiesmentioning

confidence: 99%

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Antibacterial Films Based on PVA and PVA–Chitosan Modified with Poly(Hexamethylene Guanidine)

et al. 2019

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“…In addition to the applications mentioned above, chitosan has many other potential applications. For example, the incorporating of chitosan into the polymer blend ultimately improved its strength, wettability, resistivity, and antimicrobial activity (Abraham, Soloman, & Rejini, 2016;Lewandowska, 2015;Sionkowska, 2011). Chitosan containing polymer composites can be used as coatings, paints, hydrogels, which have several ranges of applications in the industry (Dutta, 2019).…”

Section: Other Applicationsmentioning

confidence: 99%

Cationic chitosan derivatives as potential antifungals: A review of structural optimization and applications

Qin

Guo

2020

Carbohydrate Polymers

118

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The increasing resistance of pathogen fungi poses a global public concern. There are several limitations in current antifungals, including few available fungicides, severe toxicity of some fungicides, and drug resistance. Therefore, there is an urgent need to develop new antifungals with novel targets. Chitosan has been recognized as a potential antifungal substance due to its good biocompatibility, biodegradability, non-toxicity, and availability in abundance, but its applications are hampered by the low charge density results in low solubility at physiological pH. It is believed that enhancing the positive charge density of chitosan may be the most effective approach to improve both its solubility and antifungal activity. Hence, this review mainly focuses on the structural optimization strategy of cationic chitosan and the potential antifungal applications. This review also assesses and comments on the challenges, shortcomings, and prospect of cationic chitosan derivatives as antifungal therapy.

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“…6 Chitosan (CS) is a natural biopolymer which has been extensively investigated as a potential biomaterial in various composite scaffolds, owning to its biocompatibility and biodegradability. [7][8][9][10] Solutions of CS typically prepared by dissolving CS-powder in an aqueous acetic acid (1%-10% v/v), followed by heated stirring (35°C-60°C) until the CS is fully dissolved which can take between 3 and 24 h. 11,12 The above solvent system can be used to dissolve CS under ambient conditions, but dissolution time is directly proportional to temperature, 13 the ratio of CS to acetic acid 14 and the total amount of CS to be dissolved. 11 Another acid that has been used to dissolve CS is ascorbic acid, an antioxidant commonly known as Vitamin C. 15 Unlike acetic acid, ascorbic acid is able to provide protons to dissolve CS and act as a crosslinker.…”

Section: Introductionmentioning

confidence: 99%

Novel chitosan-poly(vinyl acetate) biomaterial suitable for additive manufacturing and bone tissue engineering applications

Fourie

Taute

Preez

et al. 2021

Journal of Bioactive and Compatible Polymers

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Chitosan, a biocompatible and biodegradable natural polymer, offers great promise as a biomaterial for tissue engineering applications. Chitosan scaffolds have previously been fabricated using additive manufacturing techniques, however, the use of crosslinkers, weak mechanical stability and structural resolution remain problematic. In this study Chitosan-PVAc biopolymer blends were prepared using a non-organic solvent that can prepare a three-dimensional printable biopolymer in less time than conventional methods. Prepared films were characterised using SEM, FTIR and thermogravimetric analysis. Additionally, the swelling properties, biodegradability and printability of the scaffolds were also studied. The fabricated films were biodegradable within a 3-week period and showed controllable swelling properties. Results indicated no toxicity and cells attached onto films. Additionally, hydrogels showed antibacterial activity against S. aureus, S. epidermidis and E.coli, which could potentially prevent implant related infections. Additive manufacturing simulation of PVAc composite 3% chitosan and PVAc composite 4% chitosan were able to produce a layered scaffold without using crosslinkers and therefore confirming printability. Cytocompabability were assessed using a resazurin assay and cell attachment. From these results, we concluded that the printable PVAc composite 3% chitosan and PVAc composite 4% chitosan biopolymer blends meet the requirements of a biomaterial and can potentially be used for biomedical implants.

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Characterization of chitosan composites with synthetic polymers and inorganic additives

Cited by 33 publications

References 63 publications

Antibacterial Films Based on PVA and PVA–Chitosan Modified with Poly(Hexamethylene Guanidine)

Antibacterial Films Based on PVA and PVA–Chitosan Modified with Poly(Hexamethylene Guanidine)

Cationic chitosan derivatives as potential antifungals: A review of structural optimization and applications

Novel chitosan-poly(vinyl acetate) biomaterial suitable for additive manufacturing and bone tissue engineering applications

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