2002
DOI: 10.1016/s0950-7051(01)00129-0
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Characterization of bio-chemical signals by inductive logic programming

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Cited by 12 publications
(7 citation statements)
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“…In attempts to describe the behavior of living systems, where the deductive model is not successful, the process by qualitative reasoning based on the function of molecules has shown its limits [4]. Similarly, if the properties are known, we cannot clearly deduce their function in the living cell, and from the characteristics of living cells, calculate their behavior in a given environment.…”
Section: Signaling Pathwaymentioning
confidence: 99%
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“…In attempts to describe the behavior of living systems, where the deductive model is not successful, the process by qualitative reasoning based on the function of molecules has shown its limits [4]. Similarly, if the properties are known, we cannot clearly deduce their function in the living cell, and from the characteristics of living cells, calculate their behavior in a given environment.…”
Section: Signaling Pathwaymentioning
confidence: 99%
“…Most of these reactions, which take place in a cell, are catalyzed by special molecules called enzymes. Such a large amount of data on the signaling is represented as a network, called a signaling pathway, and has been stored and maintained in a database on a large scale [4]. Fig.…”
Section: Signaling Pathwaymentioning
confidence: 99%
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“…However, no reliable technique exist to carry out real-time measurement of non-volatile substrates and metabolites in the fermentor. Several works using various approaches, lead to the conclusion that the limits of a state are linked to the singularities of biochemical signals: Steyer et al [22] (using expert system and fuzzy logic), Bakshi and Stephanopoulos [1] (using expert system and wavelets) and Doncescu et al [3] (using inductive logic) show that the beginning and the end of a state correspond to singularities of the biochemical signals measured during the process. In a fedbatch bioprocess, a physiological state can occur several times during the experience.…”
Section: Detection and Characterization Of Physiological Statesmentioning
confidence: 99%
“…In recent years, ILP has been applied successfully to a number of real-world fields, such as structure-activity for drug design [4], characterization of bio-chemical signals [5], gene regulation prediction [6] and protein-protein interactions [7,8].…”
Section: Introductionmentioning
confidence: 99%