2005
DOI: 10.1093/jac/dki076
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Characterization of antimicrobial resistance and class 1 integrons found in Escherichia coli isolates from humans and animals in Korea

Abstract: The use of antibiotics is strongly associated with antimicrobial resistance. E. coli isolates from different sources may select a specific gene cassette by antibiotic selective pressure, which results in differences in class 1 integrons. The horizontal transfer of class 1 integrons through conjugative plasmids seems to be responsible for wide dissemination of a particular type of class 1 integron.

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Cited by 202 publications
(194 citation statements)
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“…The presence of qnr gene in isolates in this study poses threat to public health. This is because qnr-plasmids are often associated with integrons and they carry multiple resistance determinants, thus providing resistance to several classes of antimicrobials including β-lactam and aminoglycoside (Kang et al 2005, Li 2005. In this study, the trimethoprim determinant dfr (A1) gene was haboured by 5 (35.7%) of the examined isolates.…”
Section: 4% a A D ( A 1 ) T E T ( A ) T E T ( B ) D F R ( A 1 ) S mentioning
confidence: 87%
“…The presence of qnr gene in isolates in this study poses threat to public health. This is because qnr-plasmids are often associated with integrons and they carry multiple resistance determinants, thus providing resistance to several classes of antimicrobials including β-lactam and aminoglycoside (Kang et al 2005, Li 2005. In this study, the trimethoprim determinant dfr (A1) gene was haboured by 5 (35.7%) of the examined isolates.…”
Section: 4% a A D ( A 1 ) T E T ( A ) T E T ( B ) D F R ( A 1 ) S mentioning
confidence: 87%
“…Such carcasses can be hubs for interactions between different host species that potentially harbour infectious agents [21]. Scavenging raptors’ diet in communal dumps are largely carcasses of farm animals which contain high rates of antimicrobial resistance [22]. The carcass dump, therefore, can facilitate intense interaction of diverse micro-biota including E. coli of human, livestock and multiple congregating, wintering wild bird species, in addition to exposure to unknown quantities and types of veterinary drugs in the carcasses.…”
Section: Introductionmentioning
confidence: 99%
“…Kang et al (2005) indicated that the predominance of the aadA1 cassette suggests that this could be the first to be acquired by an integron and/or could be more stable than the other genetic cassettes. On the other hand, the high predominance of this gene could be related to the extensive use of these aminoglucosides in the control of infectious diseases in these food-producing animals.…”
mentioning
confidence: 99%