2022
DOI: 10.1016/j.virol.2022.03.013
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Characterization of an emerging porcine respirovirus 1 isolate in the US: A novel viral vector for expression of foreign antigens

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Cited by 3 publications
(7 citation statements)
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“…PRV1 was initially identified in nasopharyngeal samples of slaughterhouse pigs in Hong Kong [ 8 ] and is currently widespread in many countries on three continents [ 3 , 9 , 10 , 13 , 14 , 15 , 17 ]. To date, two PRV1 strains have been isolated from pig nasal swabs and characterized in vitro by two research groups in the USA [ 16 , 17 ]. The pathogenesis of the first PRV1 strain (USA/MN25890NS/2016) was evaluated in conventional and colostrum-deprived/cesarean-derived pigs [ 18 ].…”
Section: Discussionmentioning
confidence: 99%
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“…PRV1 was initially identified in nasopharyngeal samples of slaughterhouse pigs in Hong Kong [ 8 ] and is currently widespread in many countries on three continents [ 3 , 9 , 10 , 13 , 14 , 15 , 17 ]. To date, two PRV1 strains have been isolated from pig nasal swabs and characterized in vitro by two research groups in the USA [ 16 , 17 ]. The pathogenesis of the first PRV1 strain (USA/MN25890NS/2016) was evaluated in conventional and colostrum-deprived/cesarean-derived pigs [ 18 ].…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, the nucleus translocation of STAT1 was blocked by these P gene products. Since several P gene products are not essential for the viability of paramyxoviruses, we will further confirm their antagonism function on IFN production and signaling pathway using our PRV1 reverse genetics [ 17 ] to construct recombinant viruses with these products knockout individually.…”
Section: Discussionmentioning
confidence: 99%
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