Characterization of an Aspergillus nidulans genomic DNA fragment conferring phosphate-non-repressible acid-phosphatase activity

The Aspergillus nidulans xprG (phoG) gene encodes a putative transcriptional activator involved in the response to nutrient limitation

“…A comparison of potential xprG gene products with the P. chrysogenum PhoG sequence (Marx et al, 1995) showed that the amino acid sequence of A. nidulans PhoG as reported by MacRae et al (1993) and recorded in the A. nidulans genome database is probably incorrect. The putative xprG gene product shown in Fig.…”

“…The phoG gene was previously isolated from an A. nidulans gene library based on its ability to enhance nonrepressible acid phosphatase activity (MacRae et al, 1993). No mutations in the phoG gene have been reported.…”

“…repressible acid phosphatase in A. nidulans (MacRae et al, 1993). The homolog of AN1414.2 was designated phoG in Penicillium chrysogenum (Marx et al, 1995).…”

Diverse interactions mediate asymmetric incompatibility by the het-6 supergene complex in Neurospora crassa

“…It has sequence similarity to NDT80, a transcription factor involved in regulating meiosis in Saccharomyces cerevisiae (Xu et al, 1995;Hepworth et al, 1998), and it was demonstrated that VIB-1 + is required for the transcription of het-6, pin-c and tol in N. crassa . VIB-1 + is also similar to the xprG (phoG) protein product in Aspergillus nidulans, which is a putative transcription factor involved in the positive regulation of phosphate-non-repressible acid phosphatase activity (MacRae et al, 1993) as well as the production of extracellular proteases that are expressed upon carbon, nitrogen or sulfur starvation (Katz et al, 2006). In fact, VIB-1 + was shown to be a positive regulator of phosphate-non-repressible acid phosphatase activity, and it is known to be differentially localized during the cell cycle of N. crassa .…”

Role of Transcription Factor CaNdt80p in Cell Separation, Hyphal Growth, and Virulence in Candida albicans

“…This family also includes VIB-1, which is a regulator of conidiation in Neurospora crassa (41) and shares a region of similarity to PhoG, a possible non-phosphate-repressible acid phosphatase in Aspergillus nidulans (23). Structural studies revealed that this family is related to the Ig-fold family of transcription factors, which includes the human TFs p53, NF-B, STAT, and AML-Runt and the Rel subfamilies (20,24).…”