Characterization of Acute Poisoning in Hospitalized Children in Southwest China

Li, Zhu; Xiao, Li; Yang, Lefu; Li, Shaojun; Tan, Liping

doi:10.3389/fped.2021.727900

Cited by 12 publications

(14 citation statements)

References 31 publications

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“…In the current study, most poisoning cases occurred in the 2–3-year-old group, followed by those in the 3–4-year-old group, which is congruent with the results of other studies [22] , [23] . Our findings are consistent with those of a survey from Southwest China that found that the top three age groups for poisoning were early childhood, preschool, and school-age children [10] . Children less than five years of age may have the greatest risk for unintentional paediatric poisoning due to factors such as exploring their surroundings, failing to distinguish between safe and harmful materials, and frequently putting their hands in their mouths.…”

Section: Discussionsupporting

confidence: 91%

“…According to the World Health Organization (WHO), poisoning is one of the top five causes of death due to unintentional injury in children [9] . Despite numerous educational and public health campaigns, poisoning remains the most common medical emergency among children [10] . Children are more vulnerable to serious injuries than adults because of their immature psychological and physical systems, lack of hazard awareness, and poor safety awareness and defence against poisons [10] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

General pattern of paediatric poisoning in Jordan during 2018–2019

ALzayadneh,

ALHadidi,

Alasasfeh

et al. 2024

Toxicology Reports

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

General pattern of paediatric poisoning in Jordan during 2018–2019

ALzayadneh,

ALHadidi,

Alasasfeh

et al. 2024

Toxicology Reports

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“…Alhaboob et al (19) demonstrated no gender preponderance for poisoning. Moreover, a male-to-female ratio of 1.2:1 among children (33), with a rising poisoning rate in males by age, has been reported. It is possible that at age < 5 years, both males and females prefer to have similar characteristics and behavioral patterns (13,34).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Clinical, Socioeconomic, and Demographic Factors in Different Poisoning Agents in Pediatric Population

Noori

Boryri

Teimouri

et al. 2022

Int J High Risk Behav Addict

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Background: Poisoning is a critical global health problem, especially among children. This study aimed to assess the epidemiological features, clinical signs, and risk factors of childhood poisoning in the southeastern region of Iran. Methods: This cross-sectional study was conducted on 636 children and adolescents admitted to the Emergency Department of Ali Ebne Abitaleb Teaching Hospital in Zahedan, Iran, within 2014 to 2020. The collected data were clinical symptoms at the time of admission, socioeconomic and demographic determinants, poisoning agents, admission to the pediatric intensive care unit (PICU), using antidote, hospital stay in days, discharge status from the hospital, self-poisoning, gender, and place of residency. The data were analyzed using SPSS software (version 18), and the level of significance was considered 0.05. Results: Opium was the most common poisoning agent with the age of 8years and femalepriority. Among poisoned subjects by chemical agents, the highlighted symptoms were respiratory distress, decreased peripheral oxygen saturation (SPO2), nausea and vomiting, fever, and a decrease in heart rate in the given order. Among poisoned subjects by medicinal agents with a decrease in SPO2, a decrease in consciousness and blood pressure was common. More frequent symptoms in children poisoned by opium were a decrease in SPO2, myosis, a decrease in heart rate, a decrease in respiratory rate, seizures, and nausea and vomiting. The factors, including antidote, gender, place of residency, poisoning by accidental events, admission to PICU, and days stayed in the hospital, were the significant factors in poisoning. Conclusions: Poisoning by opium agents was more common than other agents in Iran in lower age groups. Poisoned children by opium agents had severe symptoms with higher frequency than other agents. Antidote, gender, place of residency, poisoning by accidental events, admission to PICU, and days stayed in the hospital were significant factors in agent poisoning.

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“…Poisonings cause significant pediatric morbidity and mortality and economic burdens in the United States and globally, 1,2 corresponding to an increasing burden of disease 3 and increasing youth suicide. [4][5][6] U.S. Poison Centers receive more than 2 million exposure calls annually, over half of which are for pediatric patients.…”

Section: Introductionmentioning

confidence: 99%

Extracorporeal Membrane Oxygenation: Rescue Therapy in Pediatric Bupropion Cardiotoxicity

Olives,

Sweat,

Dorsey-Spitz

et al. 2024

J Pediatr Intensive Care

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Objective Our objective was to describe clinical characteristics and course of pediatric bupropion ingestions requiring extracorporeal membrane oxygenation (ECMO) life support. Desgin The study included a retrospective cohort of patients ≤18 years of age reported to a regional poison control (PC) system covering three states in the upper Midwest United States. All bupropion exposures ≤18 years of age, coded as receiving ECMO to treat toxicity, were included. Clinical presentation and management including ECMO are presented as descriptive statistics. Results During the study period, 4,951 bupropion exposures were reported; 1,145 (23.1%) were children. Nine patients were coded as undergoing ECMO; four (44.4%) were ≤18 years of age (median 16, range 14–17). All were treated with venoarterial ECMO. The median time from ingestion to presentation was 2.25 hours (range: 1–3.5). Median first systolic blood pressure and pulse were 100 mm Hg (range: 70–124) and 119.5 (range: 70–175). The median time from ingestion to ECMO was 17.63 hours (range: 7.25–33.75); median number of vasopressors was 2.5 (range: 2–3). All experienced multiple seizures, ventricular dysrhythmias, and hypotension. Three of four sustained cardiac arrest. All but one required transfer to an ECMO-capable facility for definitive care. Three patients survived with full neurologic recovery; one died. Conclusion Pediatric bupropion cases requiring ECMO were rare in this study. Time to initiation and duration of EMCO suggest that the variable onset of hemodynamic instability may delay ECMO initiation. It is incumbent on PCs and medical toxicologists to educate prescribers and pediatricians about bupropion's potential lethality and to consider early transfer to an ECMO center.

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Characterization of Acute Poisoning in Hospitalized Children in Southwest China

Cited by 12 publications

References 31 publications

General pattern of paediatric poisoning in Jordan during 2018–2019

General pattern of paediatric poisoning in Jordan during 2018–2019

Evaluation of Clinical, Socioeconomic, and Demographic Factors in Different Poisoning Agents in Pediatric Population

Extracorporeal Membrane Oxygenation: Rescue Therapy in Pediatric Bupropion Cardiotoxicity

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