Characterization of Acute and Chronic Toxicity of DBP to Daphnia magna

Wei, Jie; Qi, Shijie; Ban, Yanli; Wang, Yuan; Shen, Chenchen; Wang, Tianyi; Zhao, Wen; Xie, Xin

doi:10.1007/s00128-018-2391-8

Cited by 16 publications

(2 citation statements)

References 23 publications

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“…Its oral LD 50 was reported to be 3,847 and 2,278 mg/kg in male and female Sprague-Dawley rats respectively (Zarn & Tasheva, 2008). Although it has low toxicity, its residues persist in the environment and plants due to its long half-life (Liu et al, 2012). Studies on the toxicity of buprofezin to fish are scanty.…”

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Buprofezin toxication implicates health hazards in Nile tilapia ( Oreochromis niloticus )

et al. 2020

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Insecticides are used to destroy insect pests in the agro fields to increase crop productivity. Despite the regulatory restrictions, their use gradually increases because of their broad spectrum and low cost. The high levels of insecticides present in the runoff from agricultural and industrial sources flow into the water leading to the pollution of aquatic life and health hazards in non-target organisms including fish (Prusty et al., 2015). As many traditional insecticides have been banned due to environmental and health risks, compounds with low toxicity are introduced into market. The use of insect growth regulators (IGR) as insecticides is increasing as they have a selective mode of action that differs from that of broad-spectrum neurotoxic traditional insecticides. Many insect growth regulators have superior efficiency against several insect species (Zhang, Zhao, Wang, Mu, & Liu, 2017). Insecticides affecting insect chitin growth are a promising type of IGR because of their selective mechanism of action on insects and their lower toxicity to other species. However, these insecticides have harmful effects at sublethal concentrations on non-target species. Triflumuron induced oxidative stress in the liver and kidney of Balb/C mice (Timoumi et al., 2018) while diflubenzuron and flucycloxuron affected both glutathione S-transferase activity and glutathione in adult Gambusia affinis fish (Zaidi & Soltani, 2011). Buprofezin (2-tert-butylimino-3-isopropyl-5-phenyl-1,3,5-thiadiazinan-4-one) is a thiadiazine insect growth regulator affecting chitin

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confidence: 99%

Buprofezin toxication implicates health hazards in Nile tilapia ( Oreochromis niloticus )

et al. 2020

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“…Além disso, problemas na reprodução, como danos aos espermatozóides, puberdade precoce em fêmeas, anormalidades no sistema reprodutivo, má formação fetal e resultados adversos na gravidez já foram relatados em humanos e outros vertebrados . Diversos organismos modelos, como peixes, ratos, insetos, anelídeos e crustáceos, estão sendo utilizados para avaliar a toxicidade e os efeitos desses compostos e uma maior atenção tem sido direcionada aos efeitos na reprodução de invertebrados aquáticos (WEI et al, 2018). Moluscos, crustáceos e anfíbios têm se mostrado mais sensíveis a esses compostos, sendo observados efeitos biológicos em exposições com concentrações ambientalmente relevantes (na faixa de ng/L a µg/L) (OEHLMANN et al, 2009).…”

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