Characterization of a novel vasopressin/oxytocin superfamily peptide and its receptor from an ascidian, Ciona intestinalis

Kawada, Toru; Sekiguchi, Toshio; Itoh, Yoshiyuki; Ogasawara, Michio; Satake, Honoo

doi:10.1016/j.peptides.2008.05.030

Cited by 67 publications

(59 citation statements)

References 26 publications

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“…All sequences in the identified Ensembl protein family were collected from the following species (names in parenthesis indicate how the different species will be referred to henceforth): Homo sapiens (human), Mus musculus (mouse), Monodelphis domestica (opossum), Ornithorhynchus anatinus (platypus), Anolis carolinensis (anole lizard), Silurana (Xenopus) tropicalis (frog), Gallus gallus (chicken), Danio rerio (zebrafish), Oryzias latipes (medaka), Gasterosteus aculeatus (stickleback) and Takifugu rubripes (fugu). The functionally characterized Ciona instestinalis (tunicate) VP receptor sequence [22] was collected and used as query in TBLASTN searches in the Ciona intestinalis genome assembly available in the Ensembl database in order to obtain its chromosomal location and reveal possibly unidentified family members. The functionally characterized Octopus vulgaris (common octopus) sequences for OPR, CTR1 and CTR2 [21] were collected to be used as an outgroup.…”

Section: Database Searches and Sequence Annotationmentioning

confidence: 99%

The oxytocin/vasopressin receptor family has at least five members in the gnathostome lineage, inclucing two distinct V2 subtypes

Daza¹,

Lewicka²,

Larhammar³

2012

General and Comparative Endocrinology

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Section: Database Searches and Sequence Annotationmentioning

confidence: 99%

The oxytocin/vasopressin receptor family has at least five members in the gnathostome lineage, inclucing two distinct V2 subtypes

Daza¹,

Lewicka²,

Larhammar³

2012

General and Comparative Endocrinology

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“…Usually Ciona researchers use embryos; they collect eggs and sperm from the supplied animals, and the gametes are used for each experiment. Ciona adults have also been used as materials to study physiology, regeneration and biochemistry [7,22]. In 2009, the Misaki Marine Biological Station of the University of Tokyo, began supporting part of this project.…”

Section: Nbrp Supports the Breeding And Supply Of Wild-type And Stablmentioning

confidence: 99%

Ciona intestinalis and Oxycomanthus japonicus, Representatives of Marine Invertebrates

et al. 2009

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Abstract:The study of marine invertebrates is useful in various biological research fields. However, genetic analyses of these animals are limited, mainly due to difficulties in culturing them, and the genetic resources of marine invertebrates have not been organized. Recently, advances have been made in the study of two deuterostomes, an ascidian Ciona intestinalis and a feather star Oxycomanthus japonicus. The draft genome sequence of Ciona intestinalis has been determined, and its compact genome, which has less redundancy of genes compared with vertebrates, provides us with a useful experimental system for analyzing the functions of genes during development. The life cycle of Ciona intestinalis is approximately 2-3 months, and the genetic techniques including a perfect inland culture system, germline transformation with a transposon Minos, enhancer detection and insertional mutagenesis, have been established. The feather star Oxycomanthus japonicus conserves the characteristics of the basic echinoderm body plan with a segmented mesoderm, which is a fascinating characteristic for understanding the evolution of echinoderms. Oxycomanthus japonicus shows strong regeneration ability and is a suitable subject for analysis of the mechanisms of regeneration. In consideration of these features, the National BioResource Project (NBRP) has started to support the supply of wild-types, transgenic lines and inbred lines of Ciona intestinalis and Oxycomanthus japonicus.

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“…Thus, the association of neurophysins with vasopressin/oxytocin-type neuropeptides can be traced back to the common ancestor of bilaterian animals (Van Kesteren et al, 1992;Kawada et al, 2008;Stafflinger et al, 2008;Ukena et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

NG peptides: A novel family of neurophysin-associated neuropeptides

Elphick¹

2010

Gene

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Neurophysins are prohormone-derived polypeptides that are required for biosynthesis of the neurohypophyseal hormones vasopressin and oxytocin. Accordingly, mutations in the neurophysin domain of the human vasopressin gene can cause diabetes insipidus. The association of neurophysins with vasopressin/oxytocintype peptides dates back to the common ancestor of bilaterian animals and until recently it was thought to be unique. This textbook perspective on neurophysins changed with the discovery of a gene in the sea urchin Strongylocentrotus purpuratus

show abstract

Characterization of a novel vasopressin/oxytocin superfamily peptide and its receptor from an ascidian, Ciona intestinalis

Cited by 67 publications

References 26 publications

The oxytocin/vasopressin receptor family has at least five members in the gnathostome lineage, inclucing two distinct V2 subtypes

The oxytocin/vasopressin receptor family has at least five members in the gnathostome lineage, inclucing two distinct V2 subtypes

Ciona intestinalis and Oxycomanthus japonicus, Representatives of Marine Invertebrates

NG peptides: A novel family of neurophysin-associated neuropeptides

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