“…With this technique, both inorganic and organic ions, such as carboxylic acids, ,, can be separated in a single run. Other advantages, especially for atmospheric applications, include the requirement of only small sample amounts, such as a single drop of rain or fog, the broad linear detection range, and the absence of extensive sample preparation, even for complex compounds such as HULIS. , CE is usually coupled with UV–vis , or conductivity detectors, but coupling with MS has also been performed. − However, the buffers used in CE separation can interfere with the MS ionization process, and the use of sheath liquid can lead to a loss of MS sensitivity. The second problem could be avoided by coupling CE to nanospray interfaces.…”