Characterization of a novel .ALPHA.1-adrenoceptor antagonist, SGB-1534, in contractile response of isolated canine arterial and venous smooth muscle to exogenous noradrenaline: Comparison with prazosin, phentolamine and yohimbine.

Kilogram-Scale Synthesis of a Highly Selective α1-Adrenoceptor Antagonist (DL-028A)

“…Recent research in the field of α blockers has led to the discovery of several biologically specific α-adrenoceptor antagonists. − More recently, some α 1 -antagonists are being investigated for treating dysuria secondary to benign prostatic hypertrophy. , DL-028, one newly developed α 1 -antagonist, is highly selective and with LDL-lowering properties. − …”